PXD011991

PXD011991 is an original dataset announced via ProteomeXchange.

Title	The host factor: proteomic comparison of excretion/1 secretion products in Fasciola hepatica newly excysted juveniles (NEJ) derived from Lymnaea viatrix or Pseudosuccinea columella
Description	The characteristics of parasitic infections are often tied to host behavior. Although most studies have investigated definitive hosts, intermediate hosts can also play a role in shaping the distribution and accumulation of parasites. This is particularly relevant in larval stages, where intermediate host behavior could potentially interfere in the molecules secreted by the parasite into the next host during infection. To investigate this hypothesis we used a proteomic approach to analyze excretion/secretion products (ESP) from Fasciola hepatica newly excysted juveniles (NEJ) derived from two intermediate host species, Lymnaea viatrix and Pseudosuccinea columella. The two analyzed proteomes showed differences in identity, abundance, and functional classification of the proteins. Based on the differences identified between NEJ ESP samples, we can conclude that the intermediate host is a factor influencing the proteomic profile of ESP in F. hepatica
HostingRepository	PRIDE
AnnounceDate	2024-10-22
AnnouncementXML	Submission_2024-10-22_04:51:22.087.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Itabajara Vaz Jr.
SpeciesList	scientific name: Fasciola hepatica (Liver fluke); NCBI TaxID: 6192;
ModificationList	iodoacetamide derivatized residue
Instrument	Q Exactive

Revision	Datetime	Status	ChangeLog Entry
0	2018-12-10 03:10:55	ID requested
1	2019-04-30 04:25:22	announced
2	2019-05-02 07:05:01	announced	Updated publication reference for PubMed record(s): 31022392.
3	2019-08-08 03:20:30	announced	Updated publication reference for PubMed record(s): 31022392.
⏵ 4	2024-10-22 04:51:33	announced	2024-10-22: Updated project metadata.

10.1016/j.exppara.2019.04.004;

10.1016/j.dib.2019.104272;

Di Maggio LS, Tirloni L, Pinto AFM, Diedrich JK, Yates JR, Carmona C, Berasain P, da Silva Vaz I, newly excysted juveniles (NEJ) derived from different snail hosts. Data Brief, 25():104272(2019) [pubmed]

Di Maggio LS, Tirloni L, Pinto AFM, Diedrich JK, Yates JR, Carmona C, Berasain P, da Silva Vaz I, A proteomic comparison of excretion/secretion products in Fasciola hepatica newly excysted juveniles (NEJ) derived from Lymnaea viatrix or Pseudosuccinea columella. Exp Parasitol, 201():11-20(2019) [pubmed]

curator keyword: Biological, Biomedical

submitter keyword: parasite-host interaction,Fasciola hepatica, intermediate host, secretome

Itabajara da Silva Vaz Junior
contact affiliation	Centro de Biotecnologia Universidade Federal do Rio Grande do Sul
contact email	itabajara.vaz@ufrgs.br
lab head
Itabajara Vaz Jr.
contact affiliation	Universidade Federal do Rio Grande do Sul
contact email	itabajara.vaz@ufrgs.br
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2019/04/PXD011991

PRIDE project URI

• PRIDE
  1. PXD011991
     1. Label: PRIDE project
     2. Name: The host factor: proteomic comparison of excretion/1 secretion products in Fasciola hepatica newly excysted juveniles (NEJ) derived from Lymnaea viatrix or Pseudosuccinea columella