PXD011989

PXD011989 is an original dataset announced via ProteomeXchange.

Title	mRNA targeting to the human ER
Description	Besides nascent and fully synthesized precursor polypeptides, mRNAs are targeted to the human endoplasmic reticulum (ER). In contrast to precursor targeting, however, little is known about mRNA targeting. To gain novel insights into the latter process, we combined siRNA-mediated depletion of putative ER-membrane resident mRNA- receptors in HeLa cells with label-free quantitative proteomics and differential expression analysis.
HostingRepository	PRIDE
AnnounceDate	2021-09-14
AnnouncementXML	Submission_2021-09-14_08:20:18.461.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Richard Zimmermann
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	No PTMs are included in the dataset
Instrument	Q Exactive

Revision	Datetime	Status	ChangeLog Entry
0	2018-12-10 02:32:15	ID requested
⏵ 1	2021-09-14 08:20:18	announced

Dataset with its publication pending

curator keyword: Biological

submitter keyword: HeLa cells, KTN1, RRBP1

Prof. Dr. Richard Zimmermann (lab head)
contact affiliation	Medizinische Biochemie und Molekularbiologie, Universität des Saarlandes, Gebäude 44, Kirrbergerstr. 100, 66421 Homburg, Deutschland, fone +49 (0)6841 1626510, fax +49 (0)6841 1626288 Nagarjuna Nagaraj, Max Planck Institute for Biochemistry, Core facility (contact)
contact email	richard.zimmermann@uks.eu
lab head
Richard Zimmermann
contact affiliation	Saarland University
contact email	richard.zimmermann@uks.eu
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2021/06/PXD011989

PRIDE project URI

• PRIDE
  1. PXD011989
     1. Label: PRIDE project
     2. Name: mRNA targeting to the human ER