PXD011896

PXD011896 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Small cell lung cancer cell line panel whole proteome analysis
Description	We conducted a whole proteome analysis of a panel of human small cell lung cancer cell lines that were either sensitive, moderately sensitive, or insensitive to SQLE inhibition to try and identify proteome signatures of sensititivy
HostingRepository	PRIDE
AnnounceDate	2024-10-22
AnnouncementXML	Submission_2024-10-22_04:51:00.581.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Sebastian Hayes
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	TMT6plex-126 reporter+balance reagent acylated residue; iodoacetamide derivatized residue
Instrument	Orbitrap Fusion

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2018-11-30 01:18:01	ID requested
1	2019-01-09 05:16:26	announced
2	2019-01-14 04:50:03	announced	Updated publication reference for PubMed record(s): 30626880.
⏵ 3	2024-10-22 04:51:08	announced	2024-10-22: Updated project metadata.

Publication List

Mahoney CE, Pirman D, Chubukov V, Sleger T, Hayes S, Fan ZP, Allen EL, Chen Y, Huang L, Liu M, Zhang Y, McDonald G, Narayanaswamy R, Choe S, Chen Y, Gross S, Cianchetta G, Padyana AK, Murray S, Liu W, Marks KM, Murtie J, Dorsch M, Jin S, Nagaraja N, Biller SA, Roddy T, Popovici-Muller J, Smolen GA, A chemical biology screen identifies a vulnerability of neuroendocrine cancer cells to SQLE inhibition. Nat Commun, 10(1):96(2019) [pubmed]
10.1038/s41467-018-07959-4;

Mahoney CE, Pirman D, Chubukov V, Sleger T, Hayes S, Fan ZP, Allen EL, Chen Y, Huang L, Liu M, Zhang Y, McDonald G, Narayanaswamy R, Choe S, Chen Y, Gross S, Cianchetta G, Padyana AK, Murray S, Liu W, Marks KM, Murtie J, Dorsch M, Jin S, Nagaraja N, Biller SA, Roddy T, Popovici-Muller J, Smolen GA, A chemical biology screen identifies a vulnerability of neuroendocrine cancer cells to SQLE inhibition. Nat Commun, 10(1):96(2019) [pubmed]

10.1038/s41467-018-07959-4;

Keyword List

curator keyword: Biomedical
submitter keyword: LC-MSMS, tanden mass tags,Small Cell Lung Cancer

curator keyword: Biomedical

submitter keyword: LC-MSMS, tanden mass tags,Small Cell Lung Cancer

Contact List

Sebastian Hayes
contact affiliation	Agios Pharmaceuticals 88 Sidney Street Cambridge MA 02139 USA
contact email	sebastian.hayes@agios.com
lab head
Sebastian Hayes
contact affiliation	Agios Pharmaceuticals
contact email	sebastian.hayes@gmail.com
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2019/01/PXD011896
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2019/01/PXD011896

PRIDE project URI

Repository Record List

[ + ]