PXD011887

PXD011887 is an original dataset announced via ProteomeXchange.

Title	Interactome of WT and mutant PUB1 in Saccharomyces cerevisiae
Description	The yeast RNA binding protein PUB1 contains a prion-like domain (PrLD) and, when overexpressed, localizes into cytoplasmic liquid droplets and is toxic. However, truncated versions lacking the PrLD are either soluble or aggregating and do not significantly alter yeast growth. Analysis of the interactomes of WT and mutant PUB1 was analyzed to clarify the link between droplets formation and toxicity.
HostingRepository	PRIDE
AnnounceDate	2021-02-04
AnnouncementXML	Submission_2021-02-04_01:00:22.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Giulia Calloni
SpeciesList	scientific name: Saccharomyces cerevisiae (Baker's yeast); NCBI TaxID: 4932;
ModificationList	No PTMs are included in the dataset
Instrument	Q Exactive

Revision	Datetime	Status	ChangeLog Entry
0	2018-11-29 06:33:36	ID requested
⏵ 1	2021-02-04 01:00:22	announced

Gotor NL, Armaos A, Calloni G, Torrent Burgas M, Vabulas RM, De Groot NS, Tartaglia GG, RNA-binding and prion domains: the Yin and Yang of phase separation. Nucleic Acids Res, 48(17):9491-9504(2020) [pubmed]

submitter keyword: yeast, RBP, RNA granules, Prion-like domain

R. Martin Vabulas
contact affiliation	Buchmann Institute of Molecular Life Sciences and Institute of Biophysical Chemistry, Goethe University, Frankfurt am Main, Germany
contact email	vabulas@em.uni-frankfurt.de
lab head
Giulia Calloni
contact affiliation	Goethe University Frankfurt
contact email	calloni@em.uni-frankfurt.de
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2021/02/PXD011887

PRIDE project URI

• PRIDE
  1. PXD011887
     1. Label: PRIDE project
     2. Name: Interactome of WT and mutant PUB1 in Saccharomyces cerevisiae