PXD011883

PXD011883 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Quantitative proteomics of melanoma metastases derived from adherent cells or suspended cells.
Description	Detachment of melanoma and survival under anchorage-independency were recognized as initial step of tumor metastasis. Our previous studies showed altered gene expression contributed to loss of cell invasiveness, enhanced chemosensitivity, and enhanced subcutaneous tumor formation. In this study, we demonstrated that melanoma cell detachment altered vascular phenotype of melanoma metastases through disruption of expression axis of aminopeptidase-N/syndecan-1/integrin beta4, which would contribute to melanoma heterogeneity.
HostingRepository	PRIDE
AnnounceDate	2024-10-22
AnnouncementXML	Submission_2024-10-22_05:10:33.828.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Wei-Chi Ku
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	iodoacetamide derivatized residue
Instrument	LTQ Orbitrap

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2018-11-29 02:40:49	ID requested
1	2020-08-11 02:56:47	announced
⏵ 2	2024-10-22 05:10:38	announced	2024-10-22: Updated project metadata.

Publication List

Cheng YC, Ku WC, Tseng TT, Wu CP, Li M, Lee SC, 4 axis. Aging (Albany NY), 12(17):16803-16819(2020) [pubmed]
10.18632/aging.103425;

Cheng YC, Ku WC, Tseng TT, Wu CP, Li M, Lee SC, 4 axis. Aging (Albany NY), 12(17):16803-16819(2020) [pubmed]

10.18632/aging.103425;

Keyword List

submitter keyword: Human, Melanoma, Anchorage independency

submitter keyword: Human, Melanoma, Anchorage independency

Contact List

Shao-Chen Lee
contact affiliation	School of Medicine, Fu Jen Catholic University, New Taipei, Taiwan
contact email	073798@mail.fju.edu.tw
lab head
Wei-Chi Ku
contact affiliation	Fu Jen Catholic University
contact email	089052@mail.fju.edu.tw
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2020/08/PXD011883
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2020/08/PXD011883

PRIDE project URI

Repository Record List

[ + ]