PXD011872

PXD011872 is an original dataset announced via ProteomeXchange.

Title	Human Arthritic Synovial Fluid LC-MS/MS
Description	In the present study, synovial fluid (SF) samples from inflammatory arthritis (IA) patients were subjected to a label-free, mass spectrometry-based approach for the identification and quantification of IA-specific proteins and peptides. The discovery-phase project generated a warehouse of proteomic and peptidomic data providing a basis for the identification of candidates with the greatest potential to serve as novel biomarkers specific to inflammatory arthritides. A total of 11 protein candidates and 15 peptide candidates, originating from 4 proteins, were selected for follow-up studies.
HostingRepository	PRIDE
AnnounceDate	2024-10-22
AnnouncementXML	Submission_2024-10-22_04:50:53.002.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Shalini Mahendran
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	monohydroxylated residue; acetylated residue; iodoacetamide derivatized residue
Instrument	Q Exactive

Revision	Datetime	Status	ChangeLog Entry
0	2018-11-29 01:09:21	ID requested
1	2019-11-12 15:52:31	announced
⏵ 2	2024-10-22 04:50:53	announced	2024-10-22: Updated project metadata.

10.1186/s12014-019-9243-3;

Mahendran SM, Keystone EC, Krawetz RJ, Liang K, Diamandis EP, Chandran V, Elucidating the endogenous synovial fluid proteome and peptidome of inflammatory arthritis using label-free mass spectrometry. Clin Proteomics, 16():23(2019) [pubmed]

curator keyword: Biomedical

submitter keyword: Synovial fluid, Human, Arthritis, LC-MS/MS

Vinod Chandran
contact affiliation	Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, Canada Department of Clinical Biochemistry, University Health Network, Toronto, ON, Canada Centre for Prognosis Studies in Rheumatic Diseases, Krembil Research Institute, Toronto Western Hospital, University Health Network, Toronto, ON, Canada Division of Rheumatology, Department of Medicine, University of Toronto, Toronto, ON, Canada, 11Institute of Medical Science, University of Toronto, Toronto, ON, Canada
contact email	vinod.chandran@uhnresearch.ca
lab head
Shalini Mahendran
contact affiliation	University of Toronto
contact email	m.mahendran@mail.utoronto.ca
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2019/11/PXD011872

PRIDE project URI

• PRIDE
  1. PXD011872
     1. Label: PRIDE project
     2. Name: Human Arthritic Synovial Fluid LC-MS/MS