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PXD011845

PXD011845 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleHdac4 interactome in Huntington's Disease
DescriptionHdac4 has been found to modulate symptoms in Huntington's Disease (HD) mouse models through an uknown mechanism unrelated to any enzymatic activity. We investigated the protein-protein interactions to gain insight into the role of Hdac4 in HD.
HostingRepositoryPRIDE
AnnounceDate2019-05-01
AnnouncementXMLSubmission_2019-05-03_09:05:02.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterJoel Federspiel
SpeciesList scientific name: Mus musculus (Mouse); NCBI TaxID: 10090;
ModificationListphosphorylated residue; monohydroxylated residue; iodoacetamide derivatized residue; deamidated residue
InstrumentLTQ Orbitrap Velos
Dataset History
RevisionDatetimeStatusChangeLog Entry
02018-11-27 03:49:33ID requested
12019-05-01 14:27:13announced
22019-05-03 09:05:04announcedUpdated publication reference for PubMed record(s): 31040226.
Publication List
Federspiel JD, Greco TM, Lum KK, Cristea IM, Hdac4 Interactions in Huntington's Disease Viewed Through the Prism of Multiomics. Mol Cell Proteomics, 18(8 suppl 1):S92-S113(2019) [pubmed]
Keyword List
curator keyword: Biomedical
submitter keyword: mouse brain, striatum, interactome, Hdac4, Hdac5, AP-MS
Contact List
Ileana Cristea
contact affiliationDepartment of Molecular Biology, Princeton University, USA
contact emailicristea@princeton.edu
lab head
Joel Federspiel
contact affiliationPrinceton University
contact emailjoel.federspiel@princeton.edu
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
Repository Record List
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