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PXD011794

PXD011794 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleMS-rescue: A Computational Pipeline to Increase the Quality and Yield of Immunopeptidomics Experiments, part 2
DescriptionWe propose a new pipeline for the refinement of spectrum-peptide assignment, designed specifically for MHC ligand identification. By modeling the peptidome as a collection of a limited number of specificities, corresponding to the MHC alleles of the cell line, our method achieves increased sequencing depth, while at the same time removing potential experimental outliers and contaminants.
HostingRepositoryPRIDE
AnnounceDate2019-01-02
AnnouncementXMLSubmission_2019-01-02_02:21:02.xml
DigitalObjectIdentifierhttps://dx.doi.org/10.6019/PXD011794
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportSupported dataset by repository
PrimarySubmitterNicola Ternette
SpeciesList scientific name: Mus musculus (Mouse); NCBI TaxID: 10090;
ModificationListFluoro; Cation:Li; Ethyl; HCysThiolactone; Amidated; Isopropylphospho; Methyl; Cys->Dha; Hex; AEBS; Oxidation; Ethanolyl; Carboxy; Pyridylethyl; Propionamide; Phospho; Cation:Na; Deamidated; Palmitoleyl; Acetyl; Sulfo; Myristoyl; Cys->Oxoalanine; Formyl; Carbamyl; Cysteinyl; Amidine; Guanidinyl; Ammonium; Dehydrated; Biotin; Dimethyl; Dioxidation; MercaptoEthanol; Carbofuran; Trimethyl
InstrumentOrbitrap Fusion Lumos
Dataset History
RevisionDatetimeStatusChangeLog Entry
02018-11-22 01:16:44ID requested
12019-01-02 02:21:03announced
Publication List
Andreatta M, Nicastri A, Peng X, Hancock G, Dorrell L, Ternette N, Nielsen M, MS-Rescue: A Computational Pipeline to Increase the Quality and Yield of Immunopeptidomics Experiments. Proteomics, 19(4):e1800357(2019) [pubmed]
Keyword List
ProteomeXchange project tag: Biology/Disease-Driven Human Proteome Project (B/D-HPP), Human Proteome Project
curator keyword: Technical, Biomedical
submitter keyword: MHC, immunopeptidomics, TC-1
Contact List
Nicola Ternette
contact affiliationThe Jenner Institute Nuffield Department of Medicine University of Oxford
contact emailnicola.ternette@ndm.ox.ac.uk
lab head
Nicola Ternette
contact affiliationUniversity of Oxford
contact emailnicola.ternette@ndm.ox.ac.uk
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
Repository Record List
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