PXD011778

PXD011778 is an original dataset announced via ProteomeXchange.

Title	Fibroblast secretome proteomic analysis
Description	LV fibroblasts were isolated from control (day 0), and infarcted regions at day 1, day 3, and day 7 after myocardial infarction (MI). Cells were isolated in DMEM in 10% fetal bovine serum and were seeded into 6-well plates and were allowed to grow to 80% confluence in DMEM supplemented with 10% fetal bovine serum (FBS). Cells were serum starved (DMEM + 0.1% FBS) for 18 h and then media was changed and secretome was collected after 24 h. The sample sizes are n=3 biological replicates for each time point.
HostingRepository	PRIDE
AnnounceDate	2024-10-22
AnnouncementXML	Submission_2024-10-22_04:50:45.632.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Elizabeth Flynn
SpeciesList	scientific name: Mus musculus (Mouse); NCBI TaxID: 10090;
ModificationList	monohydroxylated residue; acetylated residue; iodoacetamide derivatized residue
Instrument	Q Exactive

Revision	Datetime	Status	ChangeLog Entry
0	2018-11-21 03:32:27	ID requested
1	2019-10-25 00:19:17	announced
2	2019-10-25 04:11:23	announced	2019-10-25: Updated publication reference for PubMed record(s): 30635789.
⏵ 3	2024-10-22 04:50:50	announced	2024-10-22: Updated project metadata.

10.1007/s00395-019-0715-4;

Mouton AJ, Ma Y, Rivera Gonzalez OJ, Daseke MJ, Flynn ER, Freeman TC, Garrett MR, DeLeon-Pennell KY, Lindsey ML, Fibroblast polarization over the myocardial infarction time continuum shifts roles from inflammation to angiogenesis. Basic Res Cardiol, 114(2):6(2019) [pubmed]

submitter keyword: fibroblast secretome, time course, proteome,heart

Merry Lindsey
contact affiliation	Director, Mississippi Center for Heart Research Professor, Department of Physiology and Biophysics Research Health Scientist, Research Service G.V. (Sonny) Montgomery Veterans Affairs Medical Center University of Mississippi Medical Center 2500 North State Street, Room G351-04 Jackson, MS 39216-4505
contact email	mllindsey@umc.edu
lab head
Elizabeth Flynn
contact affiliation	University of Mississippi Medical Center
contact email	EFlynn@umc.edu
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2019/10/PXD011778

PRIDE project URI

• PRIDE
  1. PXD011778
     1. Label: PRIDE project
     2. Name: Fibroblast secretome proteomic analysis