PXD011727 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | PCNA interactome - SLX4IP acts with SLX4 and XPF-ERCC1 to promote interstrand crosslink repair |
Description | We examined the complexity of replication fork composition upon DNA damage by employing a PCNA-based proteomic screen to uncover known and new players involved in replication and replication stress response. We used camptothecin or ultraviolet radiation, that lead to fork-blocking lesions, to establish a comprehensive proteomics map of the replisome under such replication stress conditions. We identified and examined two potential candidate proteins WIZ and SALL1 for their roles in DNA replication and replication stress response. |
HostingRepository | PRIDE |
AnnounceDate | 2024-10-22 |
AnnouncementXML | Submission_2024-10-22_04:50:02.800.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Zhen Chen |
SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: 9606; |
ModificationList | No PTMs are included in the dataset |
Instrument | LTQ Orbitrap Elite |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2018-11-19 07:53:58 | ID requested | |
1 | 2018-12-14 02:48:18 | announced | |
⏵ 2 | 2024-10-22 04:50:10 | announced | 2024-10-22: Updated project metadata. |
Publication List
Zhang H, Chen Z, Ye Y, Ye Z, Cao D, Xiong Y, Srivastava M, Feng X, Tang M, Wang C, Tainer JA, Chen J, SLX4IP acts with SLX4 and XPF-ERCC1 to promote interstrand crosslink repair. Nucleic Acids Res, 47(19):10181-10201(2019) [pubmed] |
10.1093/nar/gkz769; |
Keyword List
curator keyword: Biological |
submitter keyword: PCNA, BioID, interactome |
Contact List
Junjie Chen |
contact affiliation | Department of Experimental Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA |
contact email | jchen8@mdanderson.org |
lab head | |
Zhen Chen |
contact affiliation | The University of Texas MD Anderson Cancer Center |
contact email | zchen6@mdanderson.org |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2018/12/PXD011727 |
PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD011727
- Label: PRIDE project
- Name: PCNA interactome - SLX4IP acts with SLX4 and XPF-ERCC1 to promote interstrand crosslink repair