PXD011722

PXD011722 is an original dataset announced via ProteomeXchange.

Title	Proteomic And Phosphoproteomic Study Of Placenta And Fetal Liver In Mice With Diet-Induced Obesity
Description	Maternal obesity in mice negatively affects placental functionand maternal and fetal liver function. We performed a global proteomic analysis using a liquid-chromatography/mass-spectrometry system to investigate total and phosphorylated proteins in the placenta and fetal liver in a mouse model that combines maternal obesity with maternal androgen excess to identify changes in molecular pathways that might promote diseases in adulthood.
HostingRepository	PRIDE
AnnounceDate	2024-10-22
AnnouncementXML	Submission_2024-10-22_04:50:34.108.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Egor Vorontsov
SpeciesList	scientific name: Mus musculus (Mouse); NCBI TaxID: 10090;
ModificationList	TMT6plex-126 reporter+balance reagent acylated residue; phosphorylated residue; monohydroxylated residue
Instrument	Orbitrap Fusion ETD

Revision	Datetime	Status	ChangeLog Entry
0	2018-11-19 07:49:49	ID requested
1	2019-01-24 23:54:27	announced
2	2019-01-28 02:16:02	announced	Updated publication reference for PubMed record(s): 30670847.
⏵ 3	2024-10-22 04:50:34	announced	2024-10-22: Updated project metadata.

10.1038/s41366-018-0314-8;

Fornes R, Manti M, Qi X, Vorontsov E, Sihlbom C, Nystr, ö, m J, Jerlhag E, Maliqueo M, Hirschberg AL, Carlstr, ö, m M, Benrick A, Stener-Victorin E, Mice exposed to maternal androgen excess and diet-induced obesity have altered phosphorylation of catechol-O-methyltransferase in the placenta and fetal liver. Int J Obes (Lond), 43(11):2176-2188(2019) [pubmed]

curator keyword: Biomedical

submitter keyword: Phosphoproteomics, Placenta, LC-MS,Liver, Tandem Mass Tag, Mouse, Obesity

Elisabet Stener-Victorin
contact affiliation	Professor, Department of Physiology and Pharmacology, Karolinska Institutet, Stockholm, Sweden
contact email	elisabet.stener-victorin@ki.se
lab head
Egor Vorontsov
contact affiliation	Proteomics Core Facility, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden
contact email	yegor.msu@gmail.com
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2019/01/PXD011722

PRIDE project URI

• PRIDE
  1. PXD011722
     1. Label: PRIDE project
     2. Name: Proteomic And Phosphoproteomic Study Of Placenta And Fetal Liver In Mice With Diet-Induced Obesity