PXD011636

PXD011636 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Longitudinal proteomic analysis of influenza HA-reactive IgG antibody repertoire over multiple years and repeated vaccinations
Description	Longitudinal proteomic analysis of H1N1 A/California/7/2009 (CA09) hemagglutinin (HA)-reactive serum IgG antibody repertoire over 5 years and multiple (yearly) vaccinations (both pre- and post-vaccination samples) in a donor. Dataset consists of steady-state (pre-vaccination at day 0) and peak-response (2-3 weeks post-vaccination) serum IgG samples enriched by affinity chromatography against hemagglutinin protein from H1 A/California/7/2009.
HostingRepository	MassIVE
AnnounceDate	2019-03-11
AnnouncementXML	Submission_2019-03-11_14:15:41.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Supported dataset by repository
PrimarySubmitter	Andrew Horton
SpeciesList	scientific name: Homo sapiens; common name: human; NCBI TaxID: 9606;
ModificationList	Oxidation; Carbamidomethyl
Instrument	LTQ Orbitrap Velos

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2018-11-08 14:37:36	ID requested
⏵ 1	2019-03-11 14:15:42	announced

Publication List

Lee J, Paparoditis P, Horton AP, Fr, ü, hwirth A, McDaniel JR, Jung J, Boutz DR, Hussein DA, Tanno Y, Pappas L, Ippolito GC, Corti D, Lanzavecchia A, Georgiou G, Persistent Antibody Clonotypes Dominate the Serum Response to Influenza over Multiple Years and Repeated Vaccinations. Cell Host Microbe, 25(3):367-376.e5(2019) [pubmed]

Lee J, Paparoditis P, Horton AP, Fr, ü, hwirth A, McDaniel JR, Jung J, Boutz DR, Hussein DA, Tanno Y, Pappas L, Ippolito GC, Corti D, Lanzavecchia A, Georgiou G, Persistent Antibody Clonotypes Dominate the Serum Response to Influenza over Multiple Years and Repeated Vaccinations. Cell Host Microbe, 25(3):367-376.e5(2019) [pubmed]

Keyword List

submitter keyword: serum antibody profiling, Ig-Seq, LC-MS/MS, immunoglobulin, IgG, influenza, human

submitter keyword: serum antibody profiling, Ig-Seq, LC-MS/MS, immunoglobulin, IgG, influenza, human

Contact List

George Georgiou
contact affiliation	University of Texas at Austin
contact email	gg@che.utexas.edu
lab head
Andrew Horton
contact affiliation	UT Austin
contact email	ahorton@utexas.edu
dataset submitter

Full Dataset Link List

MassIVE dataset URI
Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://massive.ucsd.edu/MSV000083120

MassIVE dataset URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://massive.ucsd.edu/MSV000083120