PXD011631 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | Large-scale Profiling of ADP-Ribosylome by Chemical Proteomics |
Description | We have developed a dual metabolic incorporation of clickable NAD precursor compounds in live mammalian cells and in combination with the tandem mass tag (TMT) isobaric mass spectrometry, we have quantified the responses of thousands of endogenous proteins to clinical PARP inhibitors Olaparib and Rucaparib. |
HostingRepository | PRIDE |
AnnounceDate | 2019-05-01 |
AnnouncementXML | Submission_2019-05-01_10:07:42.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Kalesh Karunakaran |
SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: 9606; |
ModificationList | TMT6plex-126 reporter+balance reagent acylated residue |
Instrument | Orbitrap Fusion Lumos |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2018-11-08 06:08:28 | ID requested | |
⏵ 1 | 2019-05-01 10:07:42 | announced | |
Publication List
Dataset with its publication pending |
Keyword List
submitter keyword: MDA-MB-231, TMT, NAD |
Contact List
Peter A. DiMaggio |
contact affiliation | Department of Chemical Engineering, Imperial College London, UK |
contact email | p.dimaggio@imperial.ac.uk |
lab head | |
Kalesh Karunakaran |
contact affiliation | Imperial College London |
contact email | kalesh.k@imperial.ac.uk |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
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PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD011631
- Label: PRIDE project
- Name: Large-scale Profiling of ADP-Ribosylome by Chemical Proteomics