PXD011631

PXD011631 is an original dataset announced via ProteomeXchange.

Title	Large-scale Profiling of ADP-Ribosylome by Chemical Proteomics
Description	We have developed a dual metabolic incorporation of clickable NAD precursor compounds in live mammalian cells and in combination with the tandem mass tag (TMT) isobaric mass spectrometry, we have quantified the responses of thousands of endogenous proteins to clinical PARP inhibitors Olaparib and Rucaparib.
HostingRepository	PRIDE
AnnounceDate	2024-10-22
AnnouncementXML	Submission_2024-10-22_04:50:14.630.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Kalesh Karunakaran
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	TMT6plex-126 reporter+balance reagent acylated residue
Instrument	Orbitrap Fusion Lumos

Revision	Datetime	Status	ChangeLog Entry
0	2018-11-08 06:08:28	ID requested
1	2019-05-01 10:07:42	announced
⏵ 2	2024-10-22 04:50:15	announced	2024-10-22: Updated project metadata.

Dataset with its publication pending

submitter keyword: TMT,MDA-MB-231, NAD

Peter A. DiMaggio
contact affiliation	Department of Chemical Engineering, Imperial College London, UK
contact email	p.dimaggio@imperial.ac.uk
lab head
Kalesh Karunakaran
contact affiliation	Imperial College London
contact email	kalesh.k@imperial.ac.uk
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2019/05/PXD011631

PRIDE project URI

• PRIDE
  1. PXD011631
     1. Label: PRIDE project
     2. Name: Large-scale Profiling of ADP-Ribosylome by Chemical Proteomics