PXD011614
PXD011614 is an original dataset announced via ProteomeXchange.
Dataset Summary
Title | Protein-based Cardiogenic Shock Patient Classifier |
Description | Cardiogenic shock (CS) is associated with high short-term mortality and a precise CS risk stratification could guide interventions to improve patient outcome. We used mass spectrometry based proteomics to first to a discovery approach to select some biomarker canduidates and then verify them by targeted mass spectrometry (PRM). A 4-protein risk score (CS4P) was derived and validated for 90-day risk of mortality. The CS4P risk score which comprises proteins Liver-fatty acid-binding protein (L-FABP), Beta-2-microglobulin (B2MG), Fructose-bisphosphate aldolase B (ALDOB), and SerpinG1 (IC1), identified short-term mortality risk with a C-statistic of 0.83 (95% CI 0.74–0.89). |
HostingRepository | PRIDE |
AnnounceDate | 2020-11-16 |
AnnouncementXML | Submission_2020-11-16_14:47:13.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Eva Borràs |
SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: 9606; |
ModificationList | monohydroxylated residue; iodoacetamide derivatized residue |
Instrument | Orbitrap Fusion Lumos |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
---|---|---|---|
0 | 2018-11-07 08:36:52 | ID requested | |
⏵ 1 | 2020-11-16 14:47:13 | announced |
Publication List
Rueda F, Borr, à, s E, Garc, í, a-Garc, í, a C, Iborra-Egea O, Revuelta-L, ó, pez E, Harjola VP, Cediel G, Lassus J, Tarvasm, ä, ki T, Mebazaa A, Sabid, ó E, Bay, é, s-Gen, í, s A, Protein-based cardiogenic shock patient classifier. Eur Heart J, 40(32):2684-2694(2019) [pubmed] |
Keyword List
curator keyword: Biomedical |
submitter keyword: Cradiogenic shock, proteomics |
Contact List
Eduard Sabidó | |
---|---|
contact affiliation | Center for Genomic Regulation (CRG) University Pompeu Fabra (UPF) |
contact email | eduard.sabido@crg.eu |
lab head | |
Eva Borràs | |
contact affiliation | UPF |
contact email | eva.borras@upf.edu |
dataset submitter |
Full Dataset Link List
Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2020/11/PXD011614 |
PRIDE project URI |
Repository Record List
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