PXD011606

PXD011606 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Identification of HIPs in the islets of mice and non-diabetic human donors
Description	Hybrid insulin peptides (HIPs) result from the linkage of an insulin C-peptide fragment and another peptide via a traditional peptide bond to generate a sequence that is not encoded in the genome. Here, we sought to identify HIPs naturally present in the pancreatic islets of non-obese diabetic (NOD) mice, BALB/c mice, and non-diabetic human donors by mass spectrometry.
HostingRepository	PRIDE
AnnounceDate	2024-10-22
AnnouncementXML	Submission_2024-10-22_04:51:41.018.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Timothy Wiles
SpeciesList	scientific name: Mus musculus (Mouse); NCBI TaxID: 10090; scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	No PTMs are included in the dataset
Instrument	Agilent instrument model

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2018-11-07 06:25:12	ID requested
1	2019-01-07 05:30:27	announced
⏵ 2	2024-10-22 04:51:49	announced	2024-10-22: Updated project metadata.

Publication List

Wiles TA, Powell R, Michel R, Beard KS, Hohenstein A, Bradley B, Reisdorph N, Haskins K, Delong T, Identification of Hybrid Insulin Peptides (HIPs) in Mouse and Human Islets by Mass Spectrometry. J Proteome Res, 18(3):814-825(2019) [pubmed]
10.1021/acs.jproteome.8b00875;

Wiles TA, Powell R, Michel R, Beard KS, Hohenstein A, Bradley B, Reisdorph N, Haskins K, Delong T, Identification of Hybrid Insulin Peptides (HIPs) in Mouse and Human Islets by Mass Spectrometry. J Proteome Res, 18(3):814-825(2019) [pubmed]

10.1021/acs.jproteome.8b00875;

Keyword List

curator keyword: Biological
submitter keyword: hybrid insulin peptides (HIPs),pancreatic islets

curator keyword: Biological

submitter keyword: hybrid insulin peptides (HIPs),pancreatic islets

Contact List

Thomas Delong
contact affiliation	Department of Pharmaceutical Sciences Skaggs School of Pharmacy and Pharmaceutical Sciences University of Colorado
contact email	thomas.delong@ucdenver.edu
lab head
Timothy Wiles
contact affiliation	University of Colorado
contact email	timothy.wiles@ucdenver.edu
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2019/01/PXD011606
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2019/01/PXD011606

PRIDE project URI

Repository Record List

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