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PXD011446

PXD011446 is an original dataset announced via ProteomeXchange.

Dataset Summary
Titleproteome analysis of PSP and FTLD subjects
DescriptionA mild olfactory dysfunction has been observed in frontotemporal dementias (FTD). However, the underlying molecular mechanisms associated to this deficit are poorly understood. Here, we applied mass spectrometry-based quantitative proteomics to analyse pathological effects on the olfactory bulb (OB) from progressive supranuclear palsy (PSP) and frontotemporal lobar degeneration TDP43 proteinopathy (FTLD-TDP) subjects
HostingRepositoryPRIDE
AnnounceDate2022-02-15
AnnouncementXMLSubmission_2022-02-15_07:58:37.372.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterEnrique Santamaría
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationListTMT6plex-126 reporter+balance reagent acylated residue
InstrumentQ Exactive
Dataset History
RevisionDatetimeStatusChangeLog Entry
02018-10-22 09:03:34ID requested
12022-02-15 07:58:38announced
Publication List
Cartas-Cejudo P, Lach, é, n-Montes M, Fern, á, ndez-Irigoyen J, Santamar, í, a E, Tackling the Biological Meaning of the Human Olfactory Bulb Dyshomeostatic Proteome across Neurological Disorders: An Integrative Bioinformatic Approach. Int J Mol Sci, 22(21):(2021) [pubmed]
Keyword List
submitter keyword: PSP, FTLD, dementia, proteomics
Contact List
Enrique Santamaria
contact affiliationProteomics Unit, Navarrabiomed-IDISNA Proteored-ISCIII Pamplona, Spain
contact emailesantamma@navarra.es
lab head
Enrique Santamaría
contact affiliationProteomics unit
contact emailesantamma@navarra.es
dataset submitter
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Dataset FTP location
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PRIDE project URI
Repository Record List
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