PXD011446

PXD011446 is an original dataset announced via ProteomeXchange.

Title	proteome analysis of PSP and FTLD subjects
Description	A mild olfactory dysfunction has been observed in frontotemporal dementias (FTD). However, the underlying molecular mechanisms associated to this deficit are poorly understood. Here, we applied mass spectrometry-based quantitative proteomics to analyse pathological effects on the olfactory bulb (OB) from progressive supranuclear palsy (PSP) and frontotemporal lobar degeneration TDP43 proteinopathy (FTLD-TDP) subjects
HostingRepository	PRIDE
AnnounceDate	2022-02-15
AnnouncementXML	Submission_2022-02-15_07:58:37.372.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Enrique Santamaría
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	TMT6plex-126 reporter+balance reagent acylated residue
Instrument	Q Exactive

Revision	Datetime	Status	ChangeLog Entry
0	2018-10-22 09:03:34	ID requested
⏵ 1	2022-02-15 07:58:38	announced

Cartas-Cejudo P, Lach, é, n-Montes M, Fern, á, ndez-Irigoyen J, Santamar, í, a E, Tackling the Biological Meaning of the Human Olfactory Bulb Dyshomeostatic Proteome across Neurological Disorders: An Integrative Bioinformatic Approach. Int J Mol Sci, 22(21):(2021) [pubmed]

submitter keyword: PSP, FTLD, dementia, proteomics

Enrique Santamaria
contact affiliation	Proteomics Unit, Navarrabiomed-IDISNA Proteored-ISCIII Pamplona, Spain
contact email	esantamma@navarra.es
lab head
Enrique Santamaría
contact affiliation	Proteomics unit
contact email	esantamma@navarra.es
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2022/02/PXD011446

PRIDE project URI

• PRIDE
  1. PXD011446
     1. Label: PRIDE project
     2. Name: proteome analysis of PSP and FTLD subjects