PXD011357

PXD011357 is an original dataset announced via ProteomeXchange.

Title	Mucolytic activity of Akkermansia muciniphila enables Human Milk Oligosaccharides degradation.
Description	This study was conducted in order to monitor whether or not Akkermansia muciniphila was able to grow and utilize human milk and human milk oligosaccharides by deploying its mucin degrading enzymes. Interestingly, A. muciniphila was able to grow in human milk producing Short Chain Fatty Acids and degrade milk oligosaccharides (2’-fucosyllactose, 3’-siallylactose) as well as lactose.
HostingRepository	PRIDE
AnnounceDate	2020-09-07
AnnouncementXML	Submission_2020-09-06_23:56:01.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Sjef Boeren
SpeciesList	scientific name: Akkermansia muciniphila ATCC BAA-835; NCBI TaxID: 349741;
ModificationList	monohydroxylated residue; acetylated residue; iodoacetamide derivatized residue; deamidated residue
Instrument	LTQ Orbitrap

Revision	Datetime	Status	ChangeLog Entry
0	2018-10-15 05:48:56	ID requested
⏵ 1	2020-09-06 23:56:01	announced

Kostopoulos I, Elzinga J, Ottman N, Klievink JT, Blijenberg B, Aalvink S, Boeren S, Mank M, Knol J, de Vos WM, Belzer C, Akkermansia muciniphila uses human milk oligosaccharides to thrive in the early life conditions in vitro. Sci Rep, 10(1):14330(2020) [pubmed]

curator keyword: Metaproteomics, Biological

submitter keyword: Akkermansia muciniphila, microbiota, Human Milk Oligosaccharides, early life, Fucosyllactose, Sialyllactose

Sjef Boeren
contact affiliation	Wageningen University
contact email	sjef.boeren@wur.nl
lab head
Sjef Boeren
contact affiliation	Biochemistry
contact email	sjef.boeren@wur.nl
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2020/09/PXD011357

PRIDE project URI

• PRIDE
  1. PXD011357
     1. Label: PRIDE project
     2. Name: Mucolytic activity of Akkermansia muciniphila enables Human Milk Oligosaccharides degradation.