PXD011254

PXD011254 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	LOPIT-DC subcellular map of U-2 OS cells
Description	Generation of a high-resolution subcellular localisation map for the proteome of the human cancer cell line U-2 OS, using the newly developed LOPIT-DC method. Comparison of the results generated using LOPIT-DC with data generated using the well-established hyperLOPIT method and data mining regarding multi-localising proteins, signalling pathways, isoforms and large protein complexes. Integration of the two methods using transfer learning.
HostingRepository	PRIDE
AnnounceDate	2024-10-22
AnnouncementXML	Submission_2024-10-22_04:49:19.794.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Aikaterini Geladaki
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	TMT6plex-126 reporter+balance reagent acylated residue; methylthiolated residue; monohydroxylated residue; deamidated residue
Instrument	Orbitrap Fusion Lumos

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2018-10-02 07:45:05	ID requested
1	2019-01-23 01:13:51	announced
⏵ 2	2024-10-22 04:49:27	announced	2024-10-22: Updated project metadata.

Publication List

10.1038/s41467-018-08191-w;
Geladaki A, Ko, č, evar Britov, š, ek N, Breckels LM, Smith TS, Vennard OL, Mulvey CM, Crook OM, Gatto L, Lilley KS, Combining LOPIT with differential ultracentrifugation for high-resolution spatial proteomics. Nat Commun, 10(1):331(2019) [pubmed]

10.1038/s41467-018-08191-w;

Geladaki A, Ko, č, evar Britov, š, ek N, Breckels LM, Smith TS, Vennard OL, Mulvey CM, Crook OM, Gatto L, Lilley KS, Combining LOPIT with differential ultracentrifugation for high-resolution spatial proteomics. Nat Commun, 10(1):331(2019) [pubmed]

Keyword List

submitter keyword: LOPIT-DC, hyperLOPIT, cancer subcellular map, spatial proteomics

submitter keyword: LOPIT-DC, hyperLOPIT, cancer subcellular map, spatial proteomics

Contact List

Kathryn Lilley
contact affiliation	University of Cambridge, Cambridge Centre for Proteomics
contact email	ksl23@cam.ac.uk
lab head
Aikaterini Geladaki
contact affiliation	University of Cambridge
contact email	ag817@cam.ac.uk
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2019/01/PXD011254
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2019/01/PXD011254

PRIDE project URI

Repository Record List

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