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PXD011242

PXD011242 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleQuantitative Proteomics analysis of LX-2 Responses to Irradiation and TGF-β1 Description
DescriptionThe human hepatic stellate cell line LX2 was treated with 8 Gy X-ray irradiation and/or 2ng/ml recombinant human TGF-β1. The iTRAQ-based high throughput quantitative proteomic approach was used to obtain a comprehensive view of the protein ensembles affected by irradiation and/or TGF-β1 treatment on LX2. This study provides clues for further investigation of the mechanisms behind radiation-induced liver fibrosis.
HostingRepositoryPRIDE
AnnounceDate2018-12-04
AnnouncementXMLSubmission_2018-12-04_09:08:17.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterBaoying Yuan
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationListNo PTMs are included in the dataset
InstrumentOrbitrap Fusion Lumos
Dataset History
RevisionDatetimeStatusChangeLog Entry
02018-10-01 06:01:06ID requested
12018-12-04 09:08:18announced
Publication List
Yuan B, Chen Y, Wu Z, Zhang L, Zhuang Y, Zhao X, Niu H, Cheng JC, Zeng Z, 1. J Proteome Res, 18(1):508-521(2019) [pubmed]
Keyword List
submitter keyword: iTRAQ, Hepatic stellate cell, Irradiation
Contact List
Zhaochong Zeng
contact affiliationDepartment of Radiation Oncology, Zhongshan Hospital, Fudan University
contact emailzeng.zhaochong@zs-hospital.sh.cn
lab head
Baoying Yuan
contact affiliationDepartment of Radiation Oncology, Zhongshan Hospital, Fudan University
contact emailyuanbaoying32@163.com
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
Repository Record List
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