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PXD011214

PXD011214 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleUrinary glycopeptide analysis for the investigation of novel biomarkers
DescriptionThe aim of this study was to investigate the presence of intact O- and N-glycopeptides in profiles of normal human urine analyzed by capillary electrophoresis coupled to mass spectrometry (CE-MS).CE and liquid chromatography coupled to tandem mass spectrometry (CE- and LC-MS/MS) were both used to identify glycopeptide sequences. Furthermore, we estimated the abundance levels of these glycopeptides in urine from five different cancer types i.e. bladder cancer (BCa), prostate cancer (PCa), pancreatic cancer, cholangiocarcinoma (CC) and renal cell carcinoma (RCC).
HostingRepositoryPRIDE
AnnounceDate2024-10-22
AnnouncementXMLSubmission_2024-10-22_04:49:08.908.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterMartin Pejchinovski
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationListHex1HexNAc2 N4-glycosylated asparagine; Hex1HexNAc1NeuAc1 glycosylated residue; O-hexosylated threonine; O-(N-acetylamino)glucosyl-L-threonine; O-(N-acetylamino)glucosyl-L-serine; monohydroxylated residue; N-acetylneuraminylated residue
InstrumentLTQ Orbitrap Velos
Dataset History
RevisionDatetimeStatusChangeLog Entry
02018-09-28 05:20:12ID requested
12018-11-29 02:44:37announced
22024-10-22 04:49:14announced2024-10-22: Updated project metadata.
Publication List
10.1002/prca.201800111;
Belczacka I, Pejchinovski M, Krochmal M, Magalh, ã, es P, Frantzi M, Mullen W, Vlahou A, Mischak H, Jankowski V, Urinary Glycopeptide Analysis for the Investigation of Novel Biomarkers. Proteomics Clin Appl, 13(3):e1800111(2019) [pubmed]
Keyword List
curator keyword: Biomedical
submitter keyword: glycosylation,glycopeptides, urine, posttranslational modifications, protein biomarkers
Contact List
Martin Pejchinovski
contact affiliationClinical Proteomics, Mosaiques Diagnostics GmbH
contact emailpejchinovski@mosaiques-diagnostics.com
lab head
Martin Pejchinovski
contact affiliationMosaiques Diagnostics GmbH
contact emailpejchinovski@mosaiques-diagnostics.com
dataset submitter
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Dataset FTP location
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PRIDE project URI
Repository Record List
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