PXD011199

PXD011199 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Colonic proteome signature in immunoproteasome-deficient stressed mice and its relevance for irritable bowel syndrome
Description	A role for immunoproteasome in the regulation of intestinal permeability has been previously suggested both in mice during water avoidance stress (WAS) and in patients with irritable bowel syndrome (IBS). We thus aimed (i) to evaluate the colonic proteome in wild-type (wt) and β2i immunoproteasome subunit knock-out (β2i-/-) mice during WAS and (ii) to investigate the colonic expression of 49 ubiquitinated-proteins in diarrhea-predominant IBS patients (IBS-D).
HostingRepository	PRIDE
AnnounceDate	2024-10-22
AnnouncementXML	Submission_2024-10-22_04:14:44.362.xml
DigitalObjectIdentifier	https://dx.doi.org/10.6019/PXD011199
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Supported dataset by repository
PrimarySubmitter	Alexis Goichon
SpeciesList	scientific name: Mus musculus (Mouse); NCBI TaxID: 10090;
ModificationList	Oxidation; Carbamidomethyl
Instrument	6550 iFunnel Q-TOF LC/MS

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2018-09-27 02:37:43	ID requested
1	2018-12-05 02:49:25	announced
⏵ 2	2024-10-22 04:14:52	announced	2024-10-22: Updated project metadata.

Publication List

10.1021/acs.jproteome.8b00793;
10.6019/PXD011199;
Goichon A, Bahlouli W, Ghouzali I, Chan P, Vaudry D, D, é, chelotte P, Ducrott, é P, Co, ë, ffier M, Colonic Proteome Signature in Immunoproteasome-Deficient Stressed Mice and Its Relevance for Irritable Bowel Syndrome. J Proteome Res, 18(1):478-492(2019) [pubmed]

10.1021/acs.jproteome.8b00793;

10.6019/PXD011199;

Goichon A, Bahlouli W, Ghouzali I, Chan P, Vaudry D, D, é, chelotte P, Ducrott, é P, Co, ë, ffier M, Colonic Proteome Signature in Immunoproteasome-Deficient Stressed Mice and Its Relevance for Irritable Bowel Syndrome. J Proteome Res, 18(1):478-492(2019) [pubmed]

Keyword List

curator keyword: Biomedical
submitter keyword: Colonic proteome
Immunoproteasome
Irritable bowel syndrome
Water avoidance stress.

curator keyword: Biomedical

submitter keyword: Colonic proteome

Immunoproteasome

Irritable bowel syndrome

Water avoidance stress.

Contact List

Goichon A
contact affiliation	Inserm U1073
contact email	alexis.goichon@univ-rouen.fr
lab head
Alexis Goichon
contact affiliation	INSERM U1073
contact email	alexis.goichon@univ-rouen.fr
dataset submitter

Full Dataset Link List

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PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2018/12/PXD011199

PRIDE project URI

Repository Record List

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