PXD011010

PXD011010 is an original dataset announced via ProteomeXchange.

Title	Identification of proteins associated with Kv1.2 potassium channels.
Description	Kv1.2 is a prominent voltage-gated potassium channel that influences action potential generation and propagation in the central nervous system. We explored multi-protein complexes containing Kv1.2 using mass spectrometry of immunoprecipitated samples. Proteins identified as candidate interactors were prioritized based on abundance, and were screened for functional effects on Kv1.2 channels using electrophysiology.
HostingRepository	PRIDE
AnnounceDate	2018-11-04
AnnouncementXML	Submission_2018-11-04_15:51:33.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Jenny Moon
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	No PTMs are included in the dataset
Instrument	Bruker Daltonics instrument model

Revision	Datetime	Status	ChangeLog Entry
0	2018-09-05 05:43:17	ID requested
⏵ 1	2018-11-04 15:51:34	announced

Baronas VA, Yang RY, Morales LC, Sipione S, Kurata HT, Slc7a5 regulates Kv1.2 channels and modifies functional outcomes of epilepsy-linked channel mutations. Nat Commun, 9(1):4417(2018) [pubmed]

curator keyword: Biological

submitter keyword: human, Kv1.2, potassium channel, LCMSMS

Harley Takatsuna Kurata
contact affiliation	Department of Pharmacology, Alberta Diabetes Institute, University of Alberta
contact email	kurata@ualberta.ca
lab head
Jenny Moon
contact affiliation	University of British Columbia
contact email	kyungmee@mail.ubc.ca
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2018/11/PXD011010

PRIDE project URI

• PRIDE
  1. PXD011010
     1. Label: PRIDE project
     2. Name: Identification of proteins associated with Kv1.2 potassium channels.