PXD010978

PXD010978 is an original dataset announced via ProteomeXchange.

Title	D. magna CT448 protease specificity
Description	Mass developments of toxin-producing cyanobacteria are frequently observed in freshwater ecosystems due to eutrophication and global warming. These mass developments can partly be attributed to cyanobacterial toxins, such as protease inhibitors (PIs), which inhibit digestive serine proteases of Daphnia, the major herbivore of phytoplankton and cyanobacteria. To date, mechanisms of this inhibition in the gut of the crustacean Daphnia magna are not known. Here, we characterize a single serine protease, chymotrypsin 448 (CT448), which is present in the gut of the crustacean D. magna.
HostingRepository	PRIDE
AnnounceDate	2018-10-04
AnnouncementXML	Submission_2018-12-06_02:31:46.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Fatih Demir
SpeciesList	scientific name: Daphnia magna; NCBI TaxID: 35525;
ModificationList	monohydroxylated residue; acetylated residue; iodoacetamide derivatized residue
Instrument	maXis

Revision	Datetime	Status	ChangeLog Entry
0	2018-09-03 02:28:30	ID requested
1	2018-10-04 06:49:42	announced
⏵ 2	2018-12-06 02:31:47	announced	Updated publication reference for PubMed record(s): 30384195.

Lange J, Demir F, Huesgen PF, Baumann U, von Elert E, Pichlo C, Heterologous expression and characterization of a novel serine protease from Daphnia magna: A possible role in susceptibility to toxic cyanobacteria. Aquat Toxicol, 205():140-147(2018) [pubmed]

curator keyword: Biological

submitter keyword: CT448 PICS Protease Specificity

Pitter Florian Huesgen
contact affiliation	Forschungszentrum Juelich ZEA-3 Analytics Wilhelm-Johnen-Str D-52425 Juelich Germany
contact email	p.huesgen@fz-juelich.de
lab head
Fatih Demir
contact affiliation	Forschungszentrum Juelich ZEA-3 Analytics Wilhelm-Johnen-Str D-52425 Juelich
contact email	f.demir@fz-juelich.de
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2018/10/PXD010978

PRIDE project URI

• PRIDE
  1. PXD010978
     1. Label: PRIDE project
     2. Name: D. magna CT448 protease specificity