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PXD010950

PXD010950 is an original dataset announced via ProteomeXchange.

Dataset Summary
Title4 RABs proxymity labelling
DescriptionAPEX2-mediated proximity labeling was performed with 4 endosomal RABs allowed an efficient and comprehensive identification of their protein neighbors. APEX2-mediated proximity labeling was performed in triplicate. Protein enrichments obtained from all RABs were compared to APEX2-nude proximity labeling results. Finally, bioinformatic and biochemical approaches were used to confirm functional validity of RAB protein neighbor’s identification.
HostingRepositoryPRIDE
AnnounceDate2019-01-07
AnnouncementXMLSubmission_2019-01-07_05:40:00.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterTomas Del Olmo
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationListmonohydroxylated residue; acetylated residue; iodoacetamide derivatized residue
InstrumentLTQ Orbitrap
Dataset History
RevisionDatetimeStatusChangeLog Entry
02018-08-30 08:24:10ID requested
12019-01-07 05:40:02announced
Publication List
Del Olmo T, Lauzier A, Normandin C, Larcher R, Lecours M, Jean D, Lessard L, Steinberg F, Boisvert FM, Jean S, APEX2-mediated RAB proximity labeling identifies a role for RAB21 in clathrin-independent cargo sorting. EMBO Rep, 20(2):(2019) [pubmed]
Keyword List
curator keyword: Biological
submitter keyword: RABs, APEX2, Membrane trafficking, Early endosomes
Contact List
steve jean
contact affiliationuniversité de sherbrooke
contact emailsteve.jean@usherbrooke.ca
lab head
Tomas Del Olmo
contact affiliationuniversité de Sherbrooke
contact emailtomas.del.olmo@usherbrooke.ca
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
Repository Record List
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