PXD010902

PXD010902 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Rat white adipose tissue DIGE-LC-MSMS
Description	White adipose tissue is a central place to energy storage and a major endocrine organ. However, adipose molecular mechanisms have been poorly studied during prolonged fasting. To fill this gap, the aim of this study was to decipher proteomic regulations in rat adipose tissue during phase 2 (lipid mobilization) and phase 3 (protein catabolism) of prolonged fasting compared to the fed state. Specific responses reflecting adipose tissue inflammation, increased fibrinolysis and a possible protein catabolism-related energy saving mechanism were recorded during phase 3. Differences between internal and subcutaneous adipose tissues were essentially related to lipid metabolism, the response to oxidative stress and energy production. These data thus provide a molecular basis of adipose tissue responses according to the fasting stage.
HostingRepository	PRIDE
AnnounceDate	2024-10-22
AnnouncementXML	Submission_2024-10-22_05:19:16.514.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Fabrice BERTILE
SpeciesList	scientific name: Rattus norvegicus (Rat); NCBI TaxID: 10116;
ModificationList	monohydroxylated residue; acetylated residue; iodoacetamide derivatized residue
Instrument	HCTplus

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2018-08-28 07:11:36	ID requested
1	2021-02-24 01:07:16	announced
⏵ 2	2024-10-22 05:19:17	announced	2024-10-22: Updated project metadata.

Publication List

Ibrahim M, Ayoub D, Wasselin T, Van Dorsselaer A, Le Maho Y, Raclot T, Bertile F, Alterations in rat adipose tissue transcriptome and proteome in response to prolonged fasting. Biol Chem, 401(3):389-405(2020) [pubmed]
10.1515/hsz-2019-0184;

Ibrahim M, Ayoub D, Wasselin T, Van Dorsselaer A, Le Maho Y, Raclot T, Bertile F, Alterations in rat adipose tissue transcriptome and proteome in response to prolonged fasting. Biol Chem, 401(3):389-405(2020) [pubmed]

10.1515/hsz-2019-0184;

Keyword List

curator keyword: Biological
submitter keyword: LC-MSMS,Rat, fasting, white adipose tissue, 2D-DIGE

curator keyword: Biological

submitter keyword: LC-MSMS,Rat, fasting, white adipose tissue, 2D-DIGE

Contact List

Sarah Cianférani
contact affiliation	Laboratoire de Spectrométrie de Masse BioOrganique, Analytical Science department, IPHC, CNRS, Strasbourg University, UMR7178, Strasbourg, France
contact email	sarah.cianferani@unistra.fr
lab head
Fabrice BERTILE
contact affiliation	CNRS
contact email	fbertile@unistra.fr
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2021/02/PXD010902
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2021/02/PXD010902

PRIDE project URI

Repository Record List

[ + ]