PXD010891

PXD010891 is an original dataset announced via ProteomeXchange.

Title	PAXX and its paralogues synergistically direct DNA polymerase I activity in DNA repair
Description	In this study, we characterised the interactomes of PAXX and its paralogs, XLF and XRCC4, to show that these factors share the ability to interact with DNA polymerase lambda (Poll), stimulate its activityand are required for the recruitment of Poll to laser-induced DNA damage sites.
HostingRepository	PRIDE
AnnounceDate	2018-12-04
AnnouncementXML	Submission_2018-12-04_03:59:34.xml
DigitalObjectIdentifier	https://dx.doi.org/10.6019/PXD010891
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Supported dataset by repository
PrimarySubmitter	Rebekah Jukes-Jones
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	Oxidation
Instrument	Synapt MS

Revision	Datetime	Status	ChangeLog Entry
0	2018-08-28 02:21:27	ID requested
1	2018-09-24 03:11:36	announced
⏵ 2	2018-12-04 03:59:35	announced	Updated project metadata.

Dataset with its publication pending

curator keyword: Biological

submitter keyword: DNA repair, double strand breaks, NHEJ, PAXX, XLF, XRCC4, DNA-PKcs, Polymerase lambda

Michal Malewicz
contact affiliation	MRC Toxicology Unit, University of Cambridge
contact email	mzm23@mrc-tox.cam.ac.uk
lab head
Rebekah Jukes-Jones
contact affiliation	MRC Toxicology Unit
contact email	rj396@mrc-tox.cam.ac.uk
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2018/09/PXD010891

PRIDE project URI

• PRIDE
  1. PXD010891
     1. Label: PRIDE project
     2. Name: PAXX and its paralogues synergistically direct DNA polymerase I activity in DNA repair