PXD010839

PXD010839 is an original dataset announced via ProteomeXchange.

Title	coral proteomics study - Combined transcriptomic and proteomic analysis reveals a diversity of venom-related and toxin-like peptides expressed in the mat anemone Zoanthus natalensis (Cnidaria, Hexacorallia)
Description	Venoms from marine animals have been recognized as a new emerging source of peptide-based therapeutics. Several peptide toxins from sea anemone have been investigated as therapeutic leads or pharmacological tools. Venom complexity should be further confirmed using novel strategies of large-scale sequencing which integrated transcriptomics and proteomics to provide new putative proteins or peptides to be compared among species. We applied transcriptomic combining with proteomic analyses and identified six groups of peptide toxins including neurotoxin, hemostatic and hemorrhagic toxin, protease inhibitor, mixed function enzymes, venom auxiliary proteins, and peptides related to allergen and innate immunity.
HostingRepository	PRIDE
AnnounceDate	2024-10-22
AnnouncementXML	Submission_2024-10-22_04:13:13.688.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Qiwen Liao
SpeciesList	scientific name: Zoanthus sp.; NCBI TaxID: 105402;
ModificationList	phosphorylated residue; monohydroxylated residue; acetylated residue; iodoacetamide derivatized residue; deamidated residue
Instrument	Q Exactive

Revision	Datetime	Status	ChangeLog Entry
0	2018-08-21 08:08:40	ID requested
1	2019-06-24 05:52:14	announced
⏵ 2	2024-10-22 04:13:14	announced	2024-10-22: Updated project metadata.

10.1007/s00204-019-02456-z;

Liao Q, Gong G, Poon TCW, Ang IL, Lei KMK, Siu SWI, Wong CTT, R, á, dis-Baptista G, Lee SM, Combined transcriptomic and proteomic analysis reveals a diversity of venom-related and toxin-like peptides expressed in the mat anemone Zoanthus natalensis (Cnidaria, Hexacorallia). Arch Toxicol, 93(6):1745-1767(2019) [pubmed]

curator keyword: Biological, Biomedical

submitter keyword: LC-MS/MS, proteomics, coral, transcriptomics

Simon Ming-Yuen Lee
contact affiliation	University of Macau
contact email	simonlee@umac.mo
lab head
Qiwen Liao
contact affiliation	University of Macau
contact email	yb47525@umac.mo
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2019/06/PXD010839

PRIDE project URI

• PRIDE
  1. PXD010839
     1. Label: PRIDE project
     2. Name: coral proteomics study - Combined transcriptomic and proteomic analysis reveals a diversity of venom-related and toxin-like peptides expressed in the mat anemone Zoanthus natalensis (Cnidaria, Hexacorallia)