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PXD010691

DataSet Summary

  • HostingRepository: PRIDE
  • AnnounceDate: 2019-02-02
  • AnnouncementXML: Submission_2019-02-01_16:54:03.xml
  • DigitalObjectIdentifier:
  • ReviewLevel: Peer-reviewed dataset
  • DatasetOrigin: Original data
  • RepositorySupport: Unsupported dataset by repository
  • PrimarySubmitter: Sakari Joenväärä
  • Title: PLASMA PROTEOMIC ANALYSIS OF RARE BMI-DISCORDANT MONOZYGOTIC TWIN PAIRS
  • Description: The aim of the current study is to establish the effect of excess body wiehgt and liver fat on plasma proteomic profile without interference from genetic variation. Label-free proteomics (HDMSE) was performed on plasma samples of young healthy monozygotic twins who were discordant for BMI. the twins were further subdivided into groups of liver fat discordant and liver fat concordant to see the efefct fo liver fat on plasma proteomic signature.
  • SpeciesList: scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
  • ModificationList: monohydroxylated residue; iodoacetamide derivatized residue
  • Instrument: Synapt MS

Dataset History

VersionDatetimeStatusChangeLog Entry
02018-08-06 04:00:24ID requested
12019-02-01 16:54:04announced

Publication List

  1. Sahebekhtiari N, Saraswat M, Joenväärä S, Jokinen R, Lovric A, Kaye S, Mardinoglu A, Rissanen A, Kaprio J, Renkonen R, Pietiläinen KH, Plasma Proteomics Analysis Reveals Dysregulation of Complement Proteins and Inflammation in Acquired Obesity-A Study on Rare BMI-Discordant Monozygotic Twin Pairs. Proteomics Clin Appl, ():e1800173(2019) [pubmed]

Keyword List

  1. ProteomeXchange project tag: Liver (B/D-HPP)
  2. curator keyword: Biological
  3. submitter keyword: Monozygotic twins, Plasma proteomics, Label-free proteomics, Acquired Obesity, Complement activation, HDMSE

Contact List

    Risto Renkonen
    • contact affiliation: Transplantation laboratory, Faculty of Medicine, University of Helsinki, Helsinki, 00290, Finland
    • contact email: risto.renkonen@helsinki.fi
    • lab head:
    Sakari Joenväärä
    • contact affiliation: Helsinki University
    • contact email: sakari.joenvaara@helsinki.fi
    • dataset submitter:

Full Dataset Link List

  1. Dataset FTP location
  2. PRIDE project URI
Repository Record List
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