PXD010691

PXD010691 is an original dataset announced via ProteomeXchange.

Title	PLASMA PROTEOMIC ANALYSIS OF RARE BMI-DISCORDANT MONOZYGOTIC TWIN PAIRS
Description	The aim of the current study is to establish the effect of excess body wiehgt and liver fat on plasma proteomic profile without interference from genetic variation. Label-free proteomics (HDMSE) was performed on plasma samples of young healthy monozygotic twins who were discordant for BMI. the twins were further subdivided into groups of liver fat discordant and liver fat concordant to see the efefct fo liver fat on plasma proteomic signature.
HostingRepository	PRIDE
AnnounceDate	2019-02-02
AnnouncementXML	Submission_2019-02-01_16:54:03.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Sakari Joenväärä
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	monohydroxylated residue; iodoacetamide derivatized residue
Instrument	Synapt MS

Revision	Datetime	Status	ChangeLog Entry
0	2018-08-06 04:00:24	ID requested
⏵ 1	2019-02-01 16:54:04	announced

Sahebekhtiari N, Saraswat M, Joenv, ä, ä, r, ä S, Jokinen R, Lovric A, Kaye S, Mardinoglu A, Rissanen A, Kaprio J, Renkonen R, Pietil, ä, inen KH, Plasma Proteomics Analysis Reveals Dysregulation of Complement Proteins and Inflammation in Acquired Obesity-A Study on Rare BMI-Discordant Monozygotic Twin Pairs. Proteomics Clin Appl, 13(4):e1800173(2019) [pubmed]

ProteomeXchange project tag: Liver (B/D-HPP)

curator keyword: Biological

submitter keyword: Monozygotic twins, Plasma proteomics, Label-free proteomics, Acquired Obesity, Complement activation, HDMSE

Risto Renkonen
contact affiliation	Transplantation laboratory, Faculty of Medicine, University of Helsinki, Helsinki, 00290, Finland
contact email	risto.renkonen@helsinki.fi
lab head
Sakari Joenväärä
contact affiliation	Helsinki University
contact email	sakari.joenvaara@helsinki.fi
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2019/02/PXD010691

PRIDE project URI

• PRIDE
  1. PXD010691
     1. Label: PRIDE project
     2. Name: PLASMA PROTEOMIC ANALYSIS OF RARE BMI-DISCORDANT MONOZYGOTIC TWIN PAIRS