PXD010679

PXD010679 is an original dataset announced via ProteomeXchange.

Title	Sirtilin protease specificity - Sirtilins - the new old members of the vitamin K-dependent coagulation factor family
Description	Here we describe an additional member of the Vitamin K-dependent protease family comprising the Gla-EGF1-EGF2-SP domain architecture. These proteases were found in different vertebrate classes including jawless fish, cartilaginous fish, bony fish, reptiles, birds and marsupials but not in other mammals. We have investigated for the first time the homolog of the garter snake Thamnophis sirtalis and thus called these proteases ‘sirtilins’.
HostingRepository	PRIDE
AnnounceDate	2024-10-22
AnnouncementXML	Submission_2024-10-22_04:47:03.168.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Fatih Demir
SpeciesList	scientific name: Escherichia coli; NCBI TaxID: 562;
ModificationList	monohydroxylated residue; acetylated residue; iodoacetamide derivatized residue
Instrument	maXis

Revision	Datetime	Status	ChangeLog Entry
0	2018-08-03 03:52:45	ID requested
1	2019-02-22 07:21:18	announced
⏵ 2	2024-10-22 04:47:05	announced	2024-10-22: Updated project metadata.

10.1111/jth.14384;

Dahms SO, Demir F, Huesgen PF, Thorn K, Brandstetter H, K-dependent coagulation factor family. J Thromb Haemost, 17(3):470-481(2019) [pubmed]

curator keyword: Biological

submitter keyword: Sirtilin PICS protease specificity

Pitter Florian Huesgen
contact affiliation	Forschungszentrum Juelich ZEA-3 Analytics Wilhelm-Johnen-Str D-52425 Juelich Germany
contact email	p.huesgen@fz-juelich.de
lab head
Fatih Demir
contact affiliation	Forschungszentrum Juelich ZEA-3 Analytics Wilhelm-Johnen-Str D-52425 Juelich
contact email	f.demir@fz-juelich.de
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2019/02/PXD010679

PRIDE project URI

• PRIDE
  1. PXD010679
     1. Label: PRIDE project
     2. Name: Sirtilin protease specificity - Sirtilins - the new old members of the vitamin K-dependent coagulation factor family