PXD010669 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | Necator americanus secretome - In the current project we have carried out the first proteogenomic analysis of a parasitic helminth |
Description | In the current project we have carried out the first proteogenomic analysis of a parasitic helminth. This has allowed us to significantly improve the genome annotation and provide a robust characterisation of the ES proteome from the adult N. americanus. Our findings show important information on key families of proteins with both known and unknown functions which may be instrumental for host-parasite interactions, parasite survival and immune regulation. Description of these proteins is useful for informing future identification of vaccine and drug targets, diagnostics and novel therapeutics for treating autoimmune and allergic diseases. |
HostingRepository | PRIDE |
AnnounceDate | 2020-04-02 |
AnnouncementXML | Submission_2020-06-01_16:50:42.xml |
DigitalObjectIdentifier | https://dx.doi.org/10.6019/PXD010669 |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Supported dataset by repository |
PrimarySubmitter | Javier Sotillo |
SpeciesList | scientific name: Necator americanus; NCBI TaxID: 51031; |
ModificationList | No PTMs are included in the dataset |
Instrument | TripleTOF 5600 |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2018-08-03 01:39:21 | ID requested | |
⏵ 1 | 2020-06-01 16:50:43 | announced | |
Publication List
Logan J, Pearson MS, Manda SS, Choi YJ, Field M, Eichenberger RM, Mulvenna J, Nagaraj SH, Fujiwara RT, Gazzinelli-Guimaraes P, Bueno L, Mati V, Bethony JM, Mitreva M, Sotillo J, Loukas A, hookworms. PLoS Negl Trop Dis, 14(5):e0008237(2020) [pubmed] |
Keyword List
curator keyword: Biological, Biomedical |
submitter keyword: Necator americanus, secretome, proteins, proteogenomics, secretory products |
Contact List
Alex Loukas |
contact affiliation | Australian Institute of Tropical Health and Medicine James Cook University |
contact email | alex.loukas@jcu.edu.au |
lab head | |
Javier Sotillo |
contact affiliation | James Cook University |
contact email | javier.sotillo@jcu.edu.au |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2019/09/PXD010669 |
PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD010669
- Label: PRIDE project
- Name: Necator americanus secretome - In the current project we have carried out the first proteogenomic analysis of a parasitic helminth