PXD010658

PXD010658 is an original dataset announced via ProteomeXchange.

Title	Human Granulosa Cells Proteome
Description	Human granulosa cells are follicular cells surrounding the oocyte. Human granulosa cells are retrieved during in vitro fertilization a process where patients undergo hormonal stimulation including FSH and LH/hCG stimulation. Under the influence of the luteinizing hormone (LH) a process called luteinization they differentiate to luteal cells and contribute to the corpus luteum. Therefore, this cellular system is a good model for human corpus luteum (CL). To study processes within the human CL, IVF-derived GCs from patients were cultured for two to five days and then analyzed with mass spectrometry based shotgun proteomics.
HostingRepository	PRIDE
AnnounceDate	2019-03-07
AnnouncementXML	Submission_2019-03-07_06:12:05.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Jan Bernd Stöckl
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	iodoacetamide derivatized residue
Instrument	TripleTOF 5600

Revision	Datetime	Status	ChangeLog Entry
0	2018-08-02 00:35:38	ID requested
⏵ 1	2019-03-07 06:12:07	announced

Bagnjuk K, St, ö, ckl JB, Fr, ö, hlich T, Arnold GJ, Behr R, Berg U, Berg D, Kunz L, Bishop C, Xu J, Mayerhofer A, Necroptosis in primate luteolysis: a role for ceramide. Cell Death Discov, 5():67(2019) [pubmed]

curator keyword: Biological

submitter keyword: Human granulosa cells, Human Reproduction, corpus luteum, luteal cells, LC-MS/MS, Shotgun Proteomics, MaxQuant, Bottom-up

Thomas Fröhlich
contact affiliation	Thomas Fröhlich, Laboratory for Functional Genome Analysis LAFUGA, Gene Center, LMU München, Feodor-Lynen-Strasse 25, 81377 Munich, Germany
contact email	frohlich@genzentrum.lmu.de
lab head
Jan Bernd Stöckl
contact affiliation	Genzentrum der LMU München
contact email	stoeckl@genzentrum.lmu.de
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2019/03/PXD010658

PRIDE project URI

• PRIDE
  1. PXD010658
     1. Label: PRIDE project
     2. Name: Human Granulosa Cells Proteome