PXD010607

PXD010607 is an original dataset announced via ProteomeXchange.

Title	Streptomyces sp. M7 LC-MS - Streptomyces sp. M7 has demonstrated ability to remove lindane from culture media and soils
Description	Streptomyces sp. M7 has demonstrated ability to remove lindane from culture media and soils. In this study, we used MS-based label-free quantitative proteomic to understand lindane degradation and its metabolic context in Streptomyces sp. M7. We identified the proteins involved in the up-stream degradation pathway. Our results demonstrated that mineralization of lindane is feasible since proteins from an unusual down-stream degradation pathway were also identified. Degradative steps were supported by an active catabolism that supplied energy and reducing equivalents in the form of NADPH. This is the first study in which degradation steps of an organochlorine compound and metabolic context are elucidate in a biotechnological genus as Streptomyces. These results serve as basement to study other degradative actinobacteria and to improve the degradation processes of Streptomyces sp. M7.
HostingRepository	PRIDE
AnnounceDate	2020-03-12
AnnouncementXML	Submission_2020-03-12_03:42:02.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Jose Davila Costa
SpeciesList	scientific name: Streptomyces coelicolor A3(2); NCBI TaxID: 100226;
ModificationList	carbamoylated residue
Instrument	Q Exactive

Revision	Datetime	Status	ChangeLog Entry
0	2018-07-30 02:01:47	ID requested
1	2018-08-10 06:27:28	announced
⏵ 2	2020-03-12 03:42:03	announced	2020-03-12: Updated project metadata.

Dataset with its publication pending

curator keyword: Biological

submitter keyword: Streptomyces sp. M7, Lindane, Degradation

Jose Sebastian Davila Costa
contact affiliation	Actinobacteria Laboratory, PROIMI-CONICET, Tucuman-Argentina
contact email	jsdavilacosta@gmail.com
lab head
Jose Davila Costa
contact affiliation	PROIMI-CONICET
contact email	jsdavilacosta@gmail.com
dataset submitter

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PRIDE project URI

• PRIDE
  1. PXD010607
     1. Label: PRIDE project
     2. Name: Streptomyces sp. M7 LC-MS - Streptomyces sp. M7 has demonstrated ability to remove lindane from culture media and soils