PXD010594

PXD010594 is an original dataset announced via ProteomeXchange.

Title	Quantitative Microproteomics Based Characterization of the Central and Peripheral Nervous System of a Mouse Model of Krabbe Disease
Description	In-depth characterization of the proteome of the Twitcher mouse, a mouse model for Krabbe disease, to investigate the proteome changes in the Central and Peripheral Nervous System.We applied a TMT-based workflow to compare the proteomes of the corpus callosum, motor cortex and sciatic nerves of littermate Twitcher and wild-type mice.
HostingRepository	PRIDE
AnnounceDate	2019-04-04
AnnouncementXML	Submission_2019-04-04_00:10:10.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Davide Pellegrini
SpeciesList	scientific name: Mus musculus (Mouse); NCBI TaxID: 10090;
ModificationList	monohydroxylated residue; iodoacetamide derivatized residue
Instrument	Orbitrap Fusion ETD

Revision	Datetime	Status	ChangeLog Entry
0	2018-07-27 02:40:41	ID requested
⏵ 1	2019-04-04 00:10:11	announced

Pellegrini D, Del Grosso A, Angella L, Giordano N, Dilillo M, Tonazzini I, Caleo M, Cecchini M, McDonnell LA, Quantitative Microproteomics Based Characterization of the Central and Peripheral Nervous System of a Mouse Model of Krabbe Disease. Mol Cell Proteomics, 18(6):1227-1241(2019) [pubmed]

curator keyword: Biomedical

submitter keyword: Krabbe, Twitcher mouse, corpus callosum, motor cortex, sciatic nerves, TMT, proteomics

Liam A. McDonnell
contact affiliation	Fondazione Pisana per la Scienza ONLUS, 56107 San Giuliano Terme, Pisa, Italy Center for Proteomics and Metabolomics, Leiden University Medical Center, Leiden, The Netherlands
contact email	liam@fpscience.it
lab head
Davide Pellegrini
contact affiliation	Scuola Normale Superiore
contact email	davide.pellegrini@sns.it
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2019/04/PXD010594

PRIDE project URI

• PRIDE
  1. PXD010594
     1. Label: PRIDE project
     2. Name: Quantitative Microproteomics Based Characterization of the Central and Peripheral Nervous System of a Mouse Model of Krabbe Disease