PXD010572

PXD010572 is an original dataset announced via ProteomeXchange.

Title	A combined N-terminomics and shotgun proteomics approach to investigate the responses of human cells to rapamycin and zinc at the mitochondrial level
Description	This study aims investigating the impact of rapamycin and zinc at subtoxic doses on the human mitochondrial proteome. Experiments were performed on U397 monocytic cells. A dN-TOP strategy, combining shotgun proteomics and N-terminomics, was applied to study both internal and N-terminal peptides of the mitochondrial proteins.
HostingRepository	PRIDE
AnnounceDate	2019-05-14
AnnouncementXML	Submission_2019-06-14_02:38:52.xml
DigitalObjectIdentifier	https://dx.doi.org/10.6019/PXD010572
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Supported dataset by repository
PrimarySubmitter	Joanna Bons
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	No PTMs are included in the dataset
Instrument	Q Exactive

Revision	Datetime	Status	ChangeLog Entry
0	2018-07-26 03:36:31	ID requested
1	2019-05-14 01:54:13	announced
⏵ 2	2019-06-14 02:38:53	announced	Updated publication reference for PubMed record(s): 31154437.

Bons J, Macron C, Aude-Garcia C, Vaca-Jacome SA, Rompais M, Cianf, é, rani S, Carapito C, Rabilloud T, A Combined N-terminomics and Shotgun Proteomics Approach to Investigate the Responses of Human Cells to Rapamycin and Zinc at the Mitochondrial Level. Mol Cell Proteomics, 18(6):1085-1095(2019) [pubmed]

curator keyword: Biological

submitter keyword: dN-TOP strategy, N-terminome analysis, nanoLC-MS/MS, differential analysis, mitochondria

Christine Carapito
contact affiliation	IPHC (LSMBO - Laboratoire de Spectrométrie de Masse Bio-Organique), UMR 7178, Université de Strasbourg, CNRS
contact email	ccarapito@unistra.fr
lab head
Joanna Bons
contact affiliation	LSMBO - IPHC
contact email	joanna.bons@etu.unistra.fr
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2019/05/PXD010572

PRIDE project URI

• PRIDE
  1. PXD010572
     1. Label: PRIDE project
     2. Name: A combined N-terminomics and shotgun proteomics approach to investigate the responses of human cells to rapamycin and zinc at the mitochondrial level