PXD010562

PXD010562 is an original dataset announced via ProteomeXchange.

Title	Urine_AngII_proteins (Konvalinka et al. 2016)
Description	This dataset contains analyses of urine samples from 17 patients with autosomal dominant polycystic kidney disease (ADPKD or PKD), 9 patients with other chronic kidney diseases (mostly IgA nephropathy) and 11 healthy controls. We spiked in 7 heavy-labeled peptides corresponding to 6 proteins previously found to be regulated by an important bioactive peptide - angiotensin II. We then analyzed each peptide in duplicate in all urine samples to determine whether urine excretion rate of these 6 proteins reflects kidney activity of angiotensin II.
HostingRepository	PeptideAtlas
AnnounceDate	2018-07-25
AnnouncementXML	Submission_2018-07-25_10:11:10.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Supported dataset by repository
PrimarySubmitter	Ana Konvalinka
SpeciesList	scientific name: Homo sapiens; NCBI TaxID: 9606;
ModificationList	6x(13)C,4x(15)N labeled L-arginine; 6x(13)C,2x(15)N labeled L-lysine; S-carboxamidomethyl-L-cysteine
Instrument	TSQ Vantage

Revision	Datetime	Status	ChangeLog Entry
0	2018-07-25 10:07:51	ID requested
⏵ 1	2018-07-25 10:11:12	announced

Konvalinka A, Batruch I, Tokar T, Dimitromanolakis A, Reid S, Song X, Pei Y, Drabovich AP, Diamandis EP, Jurisica I, Scholey JW, Quantification of angiotensin II-regulated proteins in urine of patients with polycystic and other chronic kidney diseases by selected reaction monitoring. Clin Proteomics, 13():16(2016) [pubmed]

curator keyword: selected reaction monitoring, SRM, targeted

Ana Konvalinka
contact affiliation	University Health Network
contact email	ana.konvalinka@mail.utoronto.ca
dataset submitter
Dr. Ana Konvalinka
contact affiliation	University Health Network
contact email	ana.konvalinka@mail.utoronto.ca
lab head

PeptideAtlas dataset URI

PASSEL experiment URI

PASSEL transition group browser URI