PXD010560

PXD010560 is an original dataset announced via ProteomeXchange.

Title	Quantitative proteomic profiling of brain in Alzheimer’s disease
Description	Alzheimer's disease (AD) is the most prevalent form of dementia and the number of AD patients is expected to increase as human life expectancy improves. The deposition of β-amyloid protein (Aβ) in the extracellular matrix and neurofibrillary tangles intracellularly are pathologic hallmarks. Since the precise pathophysiology of AD has not been clearly elucidated yet, effective treatment is not available. Thus the development of valid AD biomarkers is imperative for early diagnosis and for monitoring disease progression and therapeutic responses.
HostingRepository	PRIDE
AnnounceDate	2022-04-01
AnnouncementXML	Submission_2022-04-01_09:18:54.293.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Akhilesh Pandey
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	monohydroxylated residue; iodoacetamide derivatized residue
Instrument	Orbitrap Fusion Lumos

Revision	Datetime	Status	ChangeLog Entry
0	2018-07-25 08:10:19	ID requested
⏵ 1	2022-04-01 09:18:55	announced

Sathe G, Albert M, Darrow J, Saito A, Troncoso J, Pandey A, Moghekar A, Quantitative proteomic analysis of the frontal cortex in Alzheimer's disease. J Neurochem, 156(6):988-1002(2021) [pubmed]

ProteomeXchange project tag: Human Brain Proteome Project (HUPO_HBPP) (B/D-HPP)

submitter keyword: Alzheimer's disease , Proteomics, Biomarkers

Akhilesh Pandey, M.D, Ph.D.
contact affiliation	527 Miller Research Building 733 N. Broadway Baltimore, MD 21205
contact email	pandey@jhmi.edu
lab head
Akhilesh Pandey
contact affiliation	Johns Hopkins University
contact email	pandey@jhmi.edu
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2022/04/PXD010560

PRIDE project URI

• PRIDE
  1. PXD010560
     1. Label: PRIDE project
     2. Name: Quantitative proteomic profiling of brain in Alzheimer’s disease