PXD010543

PXD010543 is an original dataset announced via ProteomeXchange.

Title	Proteomic profiling of sclerosis hippocampus revealed dysregulated packaging of vesicular neurotransmitters in temporal lobe epilepsy
Description	Proteomics and bioinformatic analyses of hippocampus were performed. High-resolution liquid chromatography coupled to tandem mass spectrometry (LC-MS/MS), in combination with TMT-6plex quantification, was applied for global protein expression analysis. The proteomics results were validated by Western blot analysis.
HostingRepository	PRIDE
AnnounceDate	2020-07-17
AnnouncementXML	Submission_2020-07-16_18:03:28.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Wei Ge
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	iodoacetamide derivatized residue
Instrument	Q Exactive

Revision	Datetime	Status	ChangeLog Entry
0	2018-07-24 07:19:51	ID requested
⏵ 1	2020-07-16 18:03:28	announced

Zhang Y, Liu Y, Jia Y, Zhao Y, Ma C, Bao X, Meng X, Dou W, Wang X, Ge W, Proteomic profiling of sclerotic hippocampus revealed dysregulated packaging of vesicular neurotransmitters in temporal lobe epilepsy. Epilepsy Res, 166():106412(2020) [pubmed]

curator keyword: Biomedical

submitter keyword: temporal lobe epilepsy, hippocampus sclerosis, proteomics, vesicle transmitters packaging, annexin

Wei Ge
contact affiliation	National Key Laboratory of Medical Molecular Biology & Department of Immunology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences, 5 Dong Dan San Tiao, Dongcheng District, Beijing 100005, China.
contact email	wei.ge@chem.ox.ac.uk
lab head
Wei Ge
contact affiliation	National Key Laboratory of Medical Molecular Biology & Department of Immunology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences
contact email	wei.ge@chem.ox.ac.uk
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2020/07/PXD010543

PRIDE project URI

• PRIDE
  1. PXD010543
     1. Label: PRIDE project
     2. Name: Proteomic profiling of sclerosis hippocampus revealed dysregulated packaging of vesicular neurotransmitters in temporal lobe epilepsy