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PXD010292

PXD010292 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleDetection and quantification of ANXA6 in blood-EVs from breast cancer patients undergoing neoadjuvant chemotherapy
DescriptionAnnexin 6 (ANXA6) is a calcium-binding, membrane-associated protein involved in membrane trafficking and cell signalling. Furthermore, ANXA6 has been recently associated to cancer progression and metastasis. The goal of the project was to assess the content of ANXA6 in EVs isolated from the plasma of 6 breast cancer patients undergoing anthracycline/taxane-based neoadjuvant chemotherapy.
HostingRepositoryPRIDE
AnnounceDate2023-11-14
AnnouncementXMLSubmission_2023-11-14_08:49:38.336.xml
DigitalObjectIdentifierhttps://dx.doi.org/10.6019/PXD010292
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportSupported dataset by repository
PrimarySubmitterChiara Cianciaruso
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationListAmmonia-loss; Phospho; Oxidation; Acetyl; Carbamidomethyl; Gln->pyro-Glu
InstrumentLTQ Orbitrap Elite
Dataset History
RevisionDatetimeStatusChangeLog Entry
02018-07-03 04:56:24ID requested
12019-01-02 01:09:08announced
22019-01-07 03:28:59announcedUpdated publication reference for PubMed record(s): 30598531.
32023-11-14 08:49:39announced2023-11-14: Updated project metadata.
Publication List
Keklikoglou I, Cianciaruso C, G, ü, ç E, Squadrito ML, Spring LM, Tazzyman S, Lambein L, Poissonnier A, Ferraro GB, Baer C, Cassar, á A, Guichard A, Iruela-Arispe ML, Lewis CE, Coussens LM, Bardia A, Jain RK, Pollard JW, De Palma M, Chemotherapy elicits pro-metastatic extracellular vesicles in breast cancer models. Nat Cell Biol, 21(2):190-202(2019) [pubmed]
10.6019/PXD010292;
Keyword List
curator keyword: Biological, Biomedical
submitter keyword: Human, ANXA6, Plasma, Extracellular vesicles
Contact List
Michele De Palma
contact affiliationHead, Angiogenesis and Tumor Microenvironment Lab The Swiss Institute for Experimental Cancer Research (ISREC) School of Life Sciences Ecole Polytechnique Fédérale de Lausanne (EPFL) (Swiss Federal Institute of Technology, Lausanne, Switzerland)
contact emailmichele.depalma@epfl.ch
lab head
Chiara Cianciaruso
contact affiliationEPFL
contact emailchiara.cianciaruso@epfl.ch
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
Repository Record List
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