PXD010292

PXD010292 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Detection and quantification of ANXA6 in blood-EVs from breast cancer patients undergoing neoadjuvant chemotherapy
Description	Annexin 6 (ANXA6) is a calcium-binding, membrane-associated protein involved in membrane trafficking and cell signalling. Furthermore, ANXA6 has been recently associated to cancer progression and metastasis. The goal of the project was to assess the content of ANXA6 in EVs isolated from the plasma of 6 breast cancer patients undergoing anthracycline/taxane-based neoadjuvant chemotherapy.
HostingRepository	PRIDE
AnnounceDate	2023-11-14
AnnouncementXML	Submission_2023-11-14_08:49:38.336.xml
DigitalObjectIdentifier	https://dx.doi.org/10.6019/PXD010292
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Supported dataset by repository
PrimarySubmitter	Chiara Cianciaruso
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	Ammonia-loss; Phospho; Oxidation; Acetyl; Carbamidomethyl; Gln->pyro-Glu
Instrument	LTQ Orbitrap Elite

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2018-07-03 04:56:24	ID requested
1	2019-01-02 01:09:08	announced
2	2019-01-07 03:28:59	announced	Updated publication reference for PubMed record(s): 30598531.
⏵ 3	2023-11-14 08:49:39	announced	2023-11-14: Updated project metadata.

Publication List

Keklikoglou I, Cianciaruso C, G, ü, ç E, Squadrito ML, Spring LM, Tazzyman S, Lambein L, Poissonnier A, Ferraro GB, Baer C, Cassar, á A, Guichard A, Iruela-Arispe ML, Lewis CE, Coussens LM, Bardia A, Jain RK, Pollard JW, De Palma M, Chemotherapy elicits pro-metastatic extracellular vesicles in breast cancer models. Nat Cell Biol, 21(2):190-202(2019) [pubmed]
10.6019/PXD010292;

Keklikoglou I, Cianciaruso C, G, ü, ç E, Squadrito ML, Spring LM, Tazzyman S, Lambein L, Poissonnier A, Ferraro GB, Baer C, Cassar, á A, Guichard A, Iruela-Arispe ML, Lewis CE, Coussens LM, Bardia A, Jain RK, Pollard JW, De Palma M, Chemotherapy elicits pro-metastatic extracellular vesicles in breast cancer models. Nat Cell Biol, 21(2):190-202(2019) [pubmed]

10.6019/PXD010292;

Keyword List

curator keyword: Biological, Biomedical
submitter keyword: Human, ANXA6, Plasma, Extracellular vesicles

curator keyword: Biological, Biomedical

submitter keyword: Human, ANXA6, Plasma, Extracellular vesicles

Contact List

Michele De Palma
contact affiliation	Head, Angiogenesis and Tumor Microenvironment Lab The Swiss Institute for Experimental Cancer Research (ISREC) School of Life Sciences Ecole Polytechnique Fédérale de Lausanne (EPFL) (Swiss Federal Institute of Technology, Lausanne, Switzerland)
contact email	michele.depalma@epfl.ch
lab head
Chiara Cianciaruso
contact affiliation	EPFL
contact email	chiara.cianciaruso@epfl.ch
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2019/01/PXD010292
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2019/01/PXD010292

PRIDE project URI

Repository Record List

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