PXD010292 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | Detection and quantification of ANXA6 in blood-EVs from breast cancer patients undergoing neoadjuvant chemotherapy |
Description | Annexin 6 (ANXA6) is a calcium-binding, membrane-associated protein involved in membrane trafficking and cell signalling. Furthermore, ANXA6 has been recently associated to cancer progression and metastasis. The goal of the project was to assess the content of ANXA6 in EVs isolated from the plasma of 6 breast cancer patients undergoing anthracycline/taxane-based neoadjuvant chemotherapy. |
HostingRepository | PRIDE |
AnnounceDate | 2023-11-14 |
AnnouncementXML | Submission_2023-11-14_08:49:38.336.xml |
DigitalObjectIdentifier | https://dx.doi.org/10.6019/PXD010292 |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Supported dataset by repository |
PrimarySubmitter | Chiara Cianciaruso |
SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: 9606; |
ModificationList | Ammonia-loss; Phospho; Oxidation; Acetyl; Carbamidomethyl; Gln->pyro-Glu |
Instrument | LTQ Orbitrap Elite |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2018-07-03 04:56:24 | ID requested | |
1 | 2019-01-02 01:09:08 | announced | |
2 | 2019-01-07 03:28:59 | announced | Updated publication reference for PubMed record(s): 30598531. |
⏵ 3 | 2023-11-14 08:49:39 | announced | 2023-11-14: Updated project metadata. |
Publication List
Keklikoglou I, Cianciaruso C, G, ü, ç E, Squadrito ML, Spring LM, Tazzyman S, Lambein L, Poissonnier A, Ferraro GB, Baer C, Cassar, á A, Guichard A, Iruela-Arispe ML, Lewis CE, Coussens LM, Bardia A, Jain RK, Pollard JW, De Palma M, Chemotherapy elicits pro-metastatic extracellular vesicles in breast cancer models. Nat Cell Biol, 21(2):190-202(2019) [pubmed] |
10.6019/PXD010292; |
Keyword List
curator keyword: Biological, Biomedical |
submitter keyword: Human, ANXA6, Plasma, Extracellular vesicles |
Contact List
Michele De Palma |
contact affiliation | Head, Angiogenesis and Tumor Microenvironment Lab The Swiss Institute for Experimental Cancer Research (ISREC) School of Life Sciences Ecole Polytechnique Fédérale de Lausanne (EPFL) (Swiss Federal Institute of Technology, Lausanne, Switzerland) |
contact email | michele.depalma@epfl.ch |
lab head | |
Chiara Cianciaruso |
contact affiliation | EPFL |
contact email | chiara.cianciaruso@epfl.ch |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
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PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD010292
- Label: PRIDE project
- Name: Detection and quantification of ANXA6 in blood-EVs from breast cancer patients undergoing neoadjuvant chemotherapy