PXD010273

PXD010273 is an original dataset announced via ProteomeXchange.

Title	Characterization of human plasma depletome from patients with schizophrenia
Description	The proteome of blood plasma is an interesting source of biomarkers and a potential way to improve treatment outcomes in psychiatric disorders. But its wide dynamic concentration range makes reducing its complexity necessary. Thus, in proteomic studies, a few of the most abundant proteins are depleted and normally discarded. This high-abundance fraction, called the depletome, however, is a source of potential biomarkers due to nonspecific bindings with low abundance proteins. In this work, we characterized the high-abundance fraction from schizophrenia patients using a shotgun mass spectrometry approach.
HostingRepository	PRIDE
AnnounceDate	2023-11-14
AnnouncementXML	Submission_2023-11-14_06:50:29.125.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Licia C. Silva-Costa
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	monohydroxylated residue; iodoacetamide derivatized residue
Instrument	Synapt MS

Revision	Datetime	Status	ChangeLog Entry
0	2018-06-29 03:34:02	ID requested
1	2019-10-22 18:06:32	announced
2	2019-12-11 07:00:02	announced	2019-12-11: Updated publication reference for DOI(s): 10.1002/sscp.201900057.
⏵ 3	2023-11-14 06:50:29	announced	2023-11-14: Updated project metadata.

Dataset with its publication pending

submitter keyword: depletion, depletome, high-definition MSE, proteomics, plasma

Daniel Martins-de-Souza
contact affiliation	Laboratory of Neuroproteomics, Unicamp, Brazil
contact email	dmsouza@unicamp.br
lab head
Licia C. Silva-Costa
contact affiliation	Unicamp
contact email	l065387@g.unicamp.br
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2019/10/PXD010273

PRIDE project URI

• PRIDE
  1. PXD010273
     1. Label: PRIDE project
     2. Name: Characterization of human plasma depletome from patients with schizophrenia