PXD010186

PXD010186 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Fish Liver Immune Response LC-MSMS
Description	High-throughput proteomics was used to determine the role of the fish liver in defense responses to bacterial infection, done using a rainbow trout (Oncorhynchus mykiss) model following infection with Aeromonas salmonicida, the causative agent of furunculosis. The vertebrate liver has multifaceted roles in innate immunity, metabolism, and growth; we hypothesize this tissue serves a dual function in supporting host defense in parallel to metabolic adjustments that promote effective immune function. While past studies have reported mRNA responses to A. salmonicida in salmonids, the impact of bacterial infectionon the liver proteome remains uncharacterized in fish.
HostingRepository	PRIDE
AnnounceDate	2024-10-22
AnnouncementXML	Submission_2024-10-22_04:46:21.456.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Dwight Causey
SpeciesList	scientific name: Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri); NCBI TaxID: 8022;
ModificationList	No PTMs are included in the dataset
Instrument	Q Exactive

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2018-06-22 02:16:15	ID requested
1	2018-10-08 04:14:35	announced
⏵ 2	2024-10-22 04:46:25	announced	2024-10-22: Updated project metadata.

Publication List

Causey DR, Pohl MAN, Stead DA, Martin SAM, Secombes CJ, Macqueen DJ, High-throughput proteomic profiling of the fish liver following bacterial infection. BMC Genomics, 19(1):719(2018) [pubmed]
10.1186/s12864-018-5092-0;

Causey DR, Pohl MAN, Stead DA, Martin SAM, Secombes CJ, Macqueen DJ, High-throughput proteomic profiling of the fish liver following bacterial infection. BMC Genomics, 19(1):719(2018) [pubmed]

10.1186/s12864-018-5092-0;

Keyword List

curator keyword: Biological
submitter keyword: LC-MSMS,Rainbow Trout, MaxQuant, Fish, Liver, Immune

curator keyword: Biological

submitter keyword: LC-MSMS,Rainbow Trout, MaxQuant, Fish, Liver, Immune

Contact List

Daniel Macqueen
contact affiliation	School of Biological Sciences, University of Aberdeen, United Kingdom
contact email	daniel.macqueen@abdn.ac.uk
lab head
Dwight Causey
contact affiliation	University of Aberdeen
contact email	d.causey@abdn.ac.uk
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2018/10/PXD010186
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2018/10/PXD010186

PRIDE project URI

Repository Record List

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