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PXD010164

PXD010164 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleRole of mTOR in regulating the extra cellular matrix
DescriptionExplored the potential role of mTOR in regulating the extra cellular matrix of TGF-b1-stimulated IPF fibroblasts grown under macromolecular crowding conditions in the presence of either CZ415 or rapamycin
HostingRepositoryPRIDE
AnnounceDate2018-11-04
AnnouncementXMLSubmission_2019-01-07_03:27:39.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterMaria Faelth Savitski
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationListTMT6plex-126 reporter+balance reagent acylated residue; methionine oxidation with neutral loss of 64 Da; acetylated residue; iodoacetamide derivatized residue
InstrumentQ Exactive
Dataset History
RevisionDatetimeStatusChangeLog Entry
02018-06-19 04:31:07ID requested
12018-11-04 14:53:50announced
22019-01-07 03:27:40announcedUpdated publication reference for PubMed record(s): 30602778.
Publication List
Woodcock HV, Eley JD, Guillotin D, Plat, é M, Nanthakumar CB, Martufi M, Peace S, Joberty G, Poeckel D, Good RB, Taylor AR, Zinn N, Redding M, Forty EJ, Hynds RE, Swanton C, Karsdal M, Maher TM, Fisher A, Bergamini G, Marshall RP, Blanchard AD, Mercer PF, Chambers RC, The mTORC1/4E-BP1 axis represents a critical signaling node during fibrogenesis. Nat Commun, 10(1):6(2019) [pubmed]
Keyword List
curator keyword: Biological
submitter keyword: mTORi, CZ415, IPF fibroblasts
Contact List
Marcus Bantscheff
contact affiliationCellzome
contact emailmarcus.x.bantscheff@gsk.com
lab head
Maria Faelth Savitski
contact affiliationCellzome
contact emailmaria.x.faelth-savitski@gsk.com
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
Repository Record List
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