PXD010164 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | Role of mTOR in regulating the extra cellular matrix |
Description | Explored the potential role of mTOR in regulating the extra cellular matrix of TGF-b1-stimulated IPF fibroblasts grown under macromolecular crowding conditions in the presence of either CZ415 or rapamycin |
HostingRepository | PRIDE |
AnnounceDate | 2018-11-04 |
AnnouncementXML | Submission_2019-01-07_03:27:39.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Maria Faelth Savitski |
SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: 9606; |
ModificationList | TMT6plex-126 reporter+balance reagent acylated residue; methionine oxidation with neutral loss of 64 Da; acetylated residue; iodoacetamide derivatized residue |
Instrument | Q Exactive |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2018-06-19 04:31:07 | ID requested | |
1 | 2018-11-04 14:53:50 | announced | |
⏵ 2 | 2019-01-07 03:27:40 | announced | Updated publication reference for PubMed record(s): 30602778. |
Publication List
Woodcock HV, Eley JD, Guillotin D, Plat, é M, Nanthakumar CB, Martufi M, Peace S, Joberty G, Poeckel D, Good RB, Taylor AR, Zinn N, Redding M, Forty EJ, Hynds RE, Swanton C, Karsdal M, Maher TM, Fisher A, Bergamini G, Marshall RP, Blanchard AD, Mercer PF, Chambers RC, The mTORC1/4E-BP1 axis represents a critical signaling node during fibrogenesis. Nat Commun, 10(1):6(2019) [pubmed] |
Keyword List
curator keyword: Biological |
submitter keyword: mTORi, CZ415, IPF fibroblasts |
Contact List
Marcus Bantscheff |
contact affiliation | Cellzome |
contact email | marcus.x.bantscheff@gsk.com |
lab head | |
Maria Faelth Savitski |
contact affiliation | Cellzome |
contact email | maria.x.faelth-savitski@gsk.com |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2018/11/PXD010164 |
PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD010164
- Label: PRIDE project
- Name: Role of mTOR in regulating the extra cellular matrix