PXD010121

PXD010121 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Analysis of Plasmodium sporozoites collected from mosquito saliva
Description	Plasmodium sporozoites are injected, in addition to saliva, into animal hosts when a female Anopheles mosquito takes a blood meal. The molecular components of saliva that interact with Plasmodium during this process are poorly characterized. Here we collected Plasmodium sporozoites directly from salivating Anopheles mosquitoes and looked for the presence of vector proteins that could be interacting with the parasites during transmission for further characterization.
HostingRepository	PRIDE
AnnounceDate	2024-10-22
AnnouncementXML	Submission_2024-10-22_04:45:58.660.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Tyler Schleicher
SpeciesList	scientific name: Plasmodium berghei ANKA; NCBI TaxID: 5823; scientific name: Anopheles stephensi (Asian malaria mosquito); NCBI TaxID: 30069; scientific name: Anopheles gambiae (African malaria mosquito); NCBI TaxID: 7165; scientific name: Plasmodium falciparum (isolate 3D7); NCBI TaxID: 36329;
ModificationList	monohydroxylated residue; iodoacetamide derivatized residue
Instrument	Q Exactive; LTQ Orbitrap Elite

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2018-06-14 01:34:08	ID requested
1	2018-10-18 02:55:25	announced
⏵ 2	2024-10-22 04:46:06	announced	2024-10-22: Updated project metadata.

Publication List

Schleicher TR, Yang J, Freudzon M, Rembisz A, Craft S, Hamilton M, Graham M, Mlambo G, Tripathi AK, Li Y, Cresswell P, Sinnis P, Dimopoulos G, Fikrig E, A mosquito salivary gland protein partially inhibits Plasmodium sporozoite cell traversal and transmission. Nat Commun, 9(1):2908(2018) [pubmed]
10.1038/s41467-018-05374-3;

Schleicher TR, Yang J, Freudzon M, Rembisz A, Craft S, Hamilton M, Graham M, Mlambo G, Tripathi AK, Li Y, Cresswell P, Sinnis P, Dimopoulos G, Fikrig E, A mosquito salivary gland protein partially inhibits Plasmodium sporozoite cell traversal and transmission. Nat Commun, 9(1):2908(2018) [pubmed]

10.1038/s41467-018-05374-3;

Keyword List

curator keyword: Biological
submitter keyword: Plasmodium, malaria, saliva, Anopheles gambiae, sporozoites

curator keyword: Biological

submitter keyword: Plasmodium, malaria, saliva, Anopheles gambiae, sporozoites

Contact List

Erol Fikrig
contact affiliation	Infectious Diseases, Department of Internal Medicine, Yale School of Medicine, Yale University, New Haven, CT 06520, USA; Howard Hughes Medical Institute, Chevy Chase, MD, 20815, USA
contact email	erol.fikrig@yale.edu
lab head
Tyler Schleicher
contact affiliation	Yale School of Medicine, Yale University
contact email	tyler.schleicher@yale.edu
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2018/10/PXD010121
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2018/10/PXD010121

PRIDE project URI

Repository Record List

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