PXD010110

PXD010110 is an original dataset announced via ProteomeXchange.

Title	Stoichiometry of Nucleosome Remodelling and Deacetylase (NuRD) complex
Description	The Nucleosome Remodeling and Deacetylase (NuRD) complex is essential for development in complex animals but has been refractory to detailed analysis because of its low abundance and resistance to recombinant production. As part of a larger project, absolute quantification using isotopically-labelled AQUA peptides was performed on natively-purified NuRD and six recombinantly-expressed NuRD subcomplexes. This is the first time the NuRD complex has been quantified using the AQUA strategy.
HostingRepository	PRIDE
AnnounceDate	2021-01-08
AnnouncementXML	Submission_2021-01-08_00:12:24.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Jason Low
SpeciesList	scientific name: Mus musculus (Mouse); NCBI TaxID: 10090; scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	monohydroxylated residue; iodoacetamide derivatized residue
Instrument	Q Exactive

Revision	Datetime	Status	ChangeLog Entry
0	2018-06-13 05:30:42	ID requested
⏵ 1	2021-01-08 00:12:25	announced

Low JKK, Silva APG, Sharifi Tabar M, Torrado M, Webb SR, Parker BL, Sana M, Smits C, Schmidberger JW, Brillault L, Jackman MJ, Williams DC, Blobel GA, Hake SB, Shepherd NE, Landsberg MJ, Mackay JP, The Nucleosome Remodeling and Deacetylase Complex Has an Asymmetric, Dynamic, and Modular Architecture. Cell Rep, 33(9):108450(2020) [pubmed]

submitter keyword: NuRD, quantitative MS, AQUA,

Joel Mackay
contact affiliation	School of Life and Environmental Sciences, University of Sydney, NSW Australia
contact email	joel.mackay@sydney.edu.au
lab head
Jason Low
contact affiliation	The University of Sydney
contact email	jason.low@sydney.edu.au
dataset submitter

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PRIDE project URI

• PRIDE
  1. PXD010110
     1. Label: PRIDE project
     2. Name: Stoichiometry of Nucleosome Remodelling and Deacetylase (NuRD) complex