PXD009914

PXD009914 is an original dataset announced via ProteomeXchange.

Title	METTL13 modulates mRNA translation through methylation of eEF1A at Lys55 and the N-terminus, part 2
Description	The experiment aimed at characterizing the methylation status of eEF1A in cells (HeLa) stressed using a panel of drugs including anisomycin, cycloheximide, 4NQO and adenosine dialdehyde (AdOx).
HostingRepository	PRIDE
AnnounceDate	2018-07-04
AnnouncementXML	Submission_2018-08-28_08:28:10.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Magnus Jakobsson
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	monomethylated residue; N6: N6; dimethylated residue
Instrument	Q Exactive HF-X

Revision	Datetime	Status	ChangeLog Entry
0	2018-05-25 07:39:07	ID requested
1	2018-07-04 06:06:17	announced
⏵ 2	2018-08-28 08:28:11	announced	Updated publication reference for PubMed record(s): 30143613.

Jakobsson ME, Ma, ł, ecki JM, Halabelian L, Nilges BS, Pinto R, Kudithipudi S, Munk S, Davydova E, Zuhairi FR, Arrowsmith CH, Jeltsch A, Leidel SA, Olsen JV, Falnes P Ø, The dual methyltransferase METTL13 targets N terminus and Lys55 of eEF1A and modulates codon-specific translation rates. Nat Commun, 9(1):3411(2018) [pubmed]

curator keyword: Biological

submitter keyword: eEF1A, PTM, methylation

Jesper V Olsen
contact affiliation	Proteomics Program, Faculty of Health and Medical Sciences, Novo Nordisk Foundation Center for Protein Research (NNF-CPR), University of Copenhagen, Denmark
contact email	Jesper.Olsen@cpr.ku.dk
lab head
Magnus Jakobsson
contact affiliation	University of Copenhagen
contact email	magnus.jakobsson@cpr.ku.dk
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2018/07/PXD009914

PRIDE project URI

• PRIDE
  1. PXD009914
     1. Label: PRIDE project
     2. Name: METTL13 modulates mRNA translation through methylation of eEF1A at Lys55 and the N-terminus, part 2