PXD009886

PXD009886 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Chapman_CCM_2018
Description	This submission contains the mass spectrometry files for the manuscript by Chapman and colleagues that characterize KRI-1 in C. elegans by affinity purification experiments of KRI-1 fused to GFP. Controls used for this experiment include ACT-5 fused to GFP and N2 worms. This dataset consists of 18 raw MS files and associated with peak lists (mzML) and mass spectrometry results (mzid) in standard formats, acquired on a Thermo Orbitrap Elite Hybrid Ion Trap-Orbitrap operated in DDA mode. Samples were generated by Eric Chapman and affinity purification, mass spectrometric acquisition and analysis was performed by Christopher Go. Raw files are deposited here in MassIVE. Brent Derry is the corresponding author of the manuscript (brent.derry@sickkids.ca); Anne-Claude Gingras should be contacted for questions on this dataset (gingras@lunenfeld.ca).
HostingRepository	MassIVE
AnnounceDate	2019-06-02
AnnouncementXML	Submission_2019-06-02_07:15:01.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Supported dataset by repository
PrimarySubmitter	Gingras Lab
SpeciesList	scientific name: Caenorhabditis elegans; NCBI TaxID: 6239;
ModificationList	deamidated L-asparagine; deamidated L-glutamine; L-methionine sulfoxide
Instrument	LTQ Orbitrap Elite

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2018-05-24 11:17:58	ID requested
⏵ 1	2019-06-02 07:30:07	announced

Publication List

Chapman EM, Lant B, Ohashi Y, Yu B, Schertzberg M, Go C, Dogra D, Koskim, ä, ki J, Girard R, Li Y, Fraser AG, Awad IA, Abdelilah-Seyfried S, Gingras AC, Derry WB, A conserved CCM complex promotes apoptosis non-autonomously by regulating zinc homeostasis. Nat Commun, 10(1):1791(2019) [pubmed]

Chapman EM, Lant B, Ohashi Y, Yu B, Schertzberg M, Go C, Dogra D, Koskim, ä, ki J, Girard R, Li Y, Fraser AG, Awad IA, Abdelilah-Seyfried S, Gingras AC, Derry WB, A conserved CCM complex promotes apoptosis non-autonomously by regulating zinc homeostasis. Nat Commun, 10(1):1791(2019) [pubmed]

Keyword List

submitter keyword: Affinity purification, Protein-protein interaction, AP-MS, KRI1_CCM1, Apoptosis, Zinc Homeostasis, Irradiation

submitter keyword: Affinity purification, Protein-protein interaction, AP-MS, KRI1_CCM1, Apoptosis, Zinc Homeostasis, Irradiation

Contact List

Anne-Claude Gingras
contact affiliation	LTRI
contact email	gingras@lunenfeld.ca
lab head
Gingras Lab
contact affiliation	Samuel Lunenfeld Research Institute
contact email	gingras@mshri.on.ca
dataset submitter

Full Dataset Link List

MassIVE dataset URI
Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://massive.ucsd.edu/MSV000082400

MassIVE dataset URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://massive.ucsd.edu/MSV000082400