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PXD009868

PXD009868 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleProstate cancer progression: From non-malignant to bone metastasisProstate cancer progression: From non-malignant to bone metastasis
DescriptionProteome characterization of gland confined prostate tumors and non-malignant prostate tissue. Whole cell protein extracts were purified from FFPE radical prostatectomy specimens for a total of 28 tumor samples and 8 adjacent non-malignant prostate tissues. Associated ProteomeXchange identifiers: PXD003430, PXD003452, PXD003515, PXD004132, PXD003615, PXD003636. Quantitative proteomic analysis of adjacent non-malignant prostate tissue (n=8) and gland confined prostate tumors (n=28) obtained from radical prostatectomy procedures; and bone metastatic prostate tumors (n=22) obtained from patients operated to relief spinal cord compression. At the time of surgery, most metastatic patients had relapsed after androgen-deprivation therapy, while 5 were previously untreated.
HostingRepositoryPRIDE
AnnounceDate2024-10-22
AnnouncementXMLSubmission_2024-10-22_04:13:37.500.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterDiego Iglesias-Gato
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationListNo PTMs are included in the dataset
InstrumentQ Exactive
Dataset History
RevisionDatetimeStatusChangeLog Entry
02018-05-23 08:24:02ID requested
12018-08-20 08:48:50announced
22018-08-21 03:35:14announcedUpdated publication reference for PubMed record(s): 30042207.
32024-10-22 04:13:38announced2024-10-22: Updated project metadata.
Publication List
10.1158/1078-0432.ccr-18-1229;
Iglesias-Gato D, Thysell E, Tyanova S, Crnalic S, Santos A, Lima TS, Geiger T, Cox J, Widmark A, Bergh A, Mann M, Flores-Morales A, Wikstr, รถ, m P, The Proteome of Prostate Cancer Bone Metastasis Reveals Heterogeneity with Prognostic Implications. Clin Cancer Res, 24(21):5433-5444(2018) [pubmed]
Keyword List
curator keyword: Biological, Biomedical
submitter keyword: Prostate cancer bone metastasis
Localized prostate cancer
Prostatectomy
Non-malignant prostate tissue
castration
CRPC
LC-MS/MS
SILAC
quantitative proteomics
Contact List
Diego Iglesias-Gato
contact affiliationUniversity of Copenhagen. Department of Drug Design and Pharmacology
contact emaildiego.iglesias@sund.ku.dk
lab head
Diego Iglesias-Gato
contact affiliationUniversity of Copenhagen
contact emaildiego.iglesias@sund.ku.dk
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
Repository Record List
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