PXD009793

PXD009793 is an original dataset announced via ProteomeXchange.

Title	Critical Vulnerabilities of the NuRD Complex for Fetal Hemoglobin Control
Description	High-resolution CRISPR functional genomics reveals critical vulnerabilities of the NuRD complex for fetal hemoglobin control
HostingRepository	PRIDE
AnnounceDate	2019-05-22
AnnouncementXML	Submission_2019-07-12_04:31:01.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Alex Kentsis
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	monohydroxylated residue; deamidated residue
Instrument	Orbitrap Fusion ETD

Revision	Datetime	Status	ChangeLog Entry
0	2018-05-16 02:57:14	ID requested
1	2019-05-22 00:13:41	announced
⏵ 2	2019-07-12 04:31:02	announced	Updated publication reference for PubMed record(s): 31253978.

Sher F, Hossain M, Seruggia D, Schoonenberg VAC, Yao Q, Cifani P, Dassama LMK, Cole MA, Ren C, Vinjamur DS, Macias-Trevino C, Luk K, McGuckin C, Schupp PG, Canver MC, Kurita R, Nakamura Y, Fujiwara Y, Wolfe SA, Pinello L, Maeda T, Kentsis A, Orkin SH, Bauer DE, Rational targeting of a NuRD subcomplex guided by comprehensive in situ mutagenesis. Nat Genet, 51(7):1149-1159(2019) [pubmed]

curator keyword: Biomedical

submitter keyword: MTA2 BioID CHD4

Alex Kentsis
contact affiliation	Molecular Pharmacology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY
contact email	kentsisresearchgroup@gmail.com
lab head
Alex Kentsis
contact affiliation	Memorial Sloan Kettering Cancer Center
contact email	kentsisresearchgroup@gmail.com
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2019/05/PXD009793

PRIDE project URI

• PRIDE
  1. PXD009793
     1. Label: PRIDE project
     2. Name: Critical Vulnerabilities of the NuRD Complex for Fetal Hemoglobin Control