PXD009699

PXD009699 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	GRX deleted Saccharomyces Cerevisiae LC-MSMS
Description	In this study, we used Saccharomyces cerevisiae to investigate the effects of GRX deletion on yeast chronological life span (CLS). Deletion of Grx1 or Grx2 shortened yeast CLS. Quantitative proteomics revealed that GRX deletion increased cellular ROS levels to activate Ras/PKA signal pathway. Our results provided new insights into mechanisms underlying aging process.
HostingRepository	PRIDE
AnnounceDate	2023-11-14
AnnouncementXML	Submission_2023-11-14_08:49:23.726.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Yan Liu
SpeciesList	scientific name: Saccharomyces cerevisiae (Baker's yeast); NCBI TaxID: 4932;
ModificationList	TMT6plex-126 reporter+balance reagent acylated residue
Instrument	Orbitrap Fusion

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2018-05-07 06:05:18	ID requested
1	2022-02-25 02:40:53	announced
⏵ 2	2023-11-14 08:49:24	announced	2023-11-14: Updated project metadata.

Publication List

Dataset with its publication pending

Dataset with its publication pending

Keyword List

curator keyword: Biological
submitter keyword: Saccharomyces Cerevisiae GRX ROS LC-MSMS

curator keyword: Biological

submitter keyword: Saccharomyces Cerevisiae GRX ROS LC-MSMS

Contact List

Haiteng Deng
contact affiliation	MOE Key Laboratory of Bioinformatics, School of Life Sciences, Tsinghua University, Beijing, China
contact email	dht@mail.tsinghua.edu.cn
lab head
Yan Liu
contact affiliation	Tsinghua University
contact email	liuyanwisdom@163.com
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2022/02/PXD009699
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2022/02/PXD009699

PRIDE project URI

Repository Record List

[ + ]