PXD009557

PXD009557 is an original dataset announced via ProteomeXchange.

Title	Proteome of ZIKV-infected and NS4B-transduced hNPC (H/PF/2013)
Description	To investigate the effects of ZIKV infection or ZIKV-NS4B-transduction on the global proteome scale at early stages of hNPC differentiation into neurons, hNPC cells were infected with ZIKV (Asian strain: H/PF/2013; MOI=0.01) or transduced with ZIKV-NS4B or HCV-NS4B and one day later cells were either left under proliferative conditions or neuronal differentiation was induced with ROCK inhibitors treatment and growth factors withdrawals. Five days later samples were harvested and processed for quantitative label-free proteomics.
HostingRepository	PRIDE
AnnounceDate	2018-09-03
AnnouncementXML	Submission_2018-09-05_04:31:57.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Pietro Scaturro
SpeciesList	scientific name: Zika virus ZIKV/H. sapiens/FrenchPolynesia/10087PF/2013; NCBI TaxID: 2043570; scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	acetylated residue; iodoacetamide derivatized residue
Instrument	Q Exactive

Revision	Datetime	Status	ChangeLog Entry
0	2018-04-20 05:57:41	ID requested
1	2018-09-03 01:16:28	announced
⏵ 2	2018-09-05 04:31:58	announced	Updated publication reference for PubMed record(s): 30177828.

Scaturro P, Stukalov A, Haas DA, Cortese M, Draganova K, P, ł, aszczyca A, Bartenschlager R, G, ö, tz M, Pichlmair A, An orthogonal proteomic survey uncovers novel Zika virus host factors. Nature, 561(7722):253-257(2018) [pubmed]

curator keyword: Biological, Biomedical

submitter keyword: hNPC, ZIKV, proteome, differentiation

Andreas Pichlmair
contact affiliation	Immunopathology of Virus Infections Institute of Virology Technical University of Munich Munich, Germany
contact email	andreas.pichlmair@tum.de
lab head
Pietro Scaturro
contact affiliation	Technical University Munich, Department of Virology
contact email	pietro.scaturro@tum.de
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2018/09/PXD009557

PRIDE project URI

• PRIDE
  1. PXD009557
     1. Label: PRIDE project
     2. Name: Proteome of ZIKV-infected and NS4B-transduced hNPC (H/PF/2013)