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PXD009554

PXD009554 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleMajor metabolic pathway alterations in the rat myocardium during development of Type 2 diabetes mellitus, part 1
DescriptionThe understanding of protein alterations in the diabetic heart is of vital importance because of increased risk of cardiovascular co-morbidities. The study aims at elucidating metabolic pathways in the diabetic rat heart during development of Type 2 diabetes mellitus using MS based proteomics.
HostingRepositoryPRIDE
AnnounceDate2024-10-22
AnnouncementXMLSubmission_2024-10-22_04:44:33.945.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterAnders Edhager
SpeciesList scientific name: Rattus norvegicus (Rat); NCBI TaxID: 10116;
ModificationListTMT6plex-126 reporter+balance reagent acylated residue; monohydroxylated residue; iodoacetamide derivatized residue
InstrumentQ Exactive
Dataset History
RevisionDatetimeStatusChangeLog Entry
02018-04-20 02:32:10ID requested
12018-06-26 04:01:03announced
22024-10-22 04:44:34announced2024-10-22: Updated project metadata.
Publication List
10.1021/acs.jproteome.8b00276;
Edhager AV, Povlsen JA, L, ø, fgren B, B, ø, tker HE, Palmfeldt J, Proteomics of the Rat Myocardium during Development of Type 2 Diabetes Mellitus Reveals Progressive Alterations in Major Metabolic Pathways. J Proteome Res, 17(7):2521-2532(2018) [pubmed]
Keyword List
curator keyword: Biomedical
submitter keyword: Heart, Type 2 diabetes mellitus, proteomics, mass spectrometry, LC-MS/MS, Rattus
Contact List
Johan Palmfeldt
contact affiliationResearch Unit for Molecular Medicine, Department of Clinical Medicine, Aarhus University, Denmark
contact emailjohan.palmfeldt@clin.au.dk
lab head
Anders Edhager
contact affiliationAarhus University
contact emailave@clin.au.dk
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
Repository Record List
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